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Study · Animal study (in vivo) · pig · 2022

9 results

Effects of kisspeptin-10 on the reproductive performance of sows in a fixed-time artificial insemination programme.

Qin YS, Bai JH, Zhang SL, Dai JG, Xu XL, Feng T, Song YQ, Xiao LL, Liu Y

Animal : an international journal of animal bioscience15 Apr 2022Cited by 4 (Europe PMC)

PMID35436648 (opens in a new tab)DOI10.1016/j.animal.2022.100509 (opens in a new tab)PepBankPUB-35436648
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study9

9 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In weaned sows, the total number of piglets born did not differ among the GnRH and kisspeptin‑10 groups.

    In plain wordsIn sows, the number of piglets born after kisspeptin‑10 was not different from that after GnRH.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeTotal piglets born
    Study

    pign = 198

    weaned sows in a fixed-time artificial insemination programme
    Comparator
    GnRH (gonadorelin) group
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.5 or 1 mgAs given in this study (pig).

    Source sentences

    Summary
    Moreover, the total numbers of piglets born and those born alive did not differ among the three groups.
    2 context sentences
    Summary · context
    One hundred ninety-eight weaned sows were divided into three groups at random.
    Summary · context
    A FTAI-GnRH group of sows (n = 98) received 100 µg (2 mL) gonadotropin-releasing hormone (GnRH; gonadorelin) by intramuscular injection at 96 h after weaning (t = 0 h); FTAI-KPL (KPL: low-dose KP-10, n = 50), and FTAI-KPH groups of sows (KPH: high-dose KP-10, n = 50) received 0.5 or 1 mg KP-10 (2 mL…
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In weaned sows, the number of piglets born alive did not differ among the GnRH and kisspeptin‑10 groups.

    In plain wordsIn sows, the number of live piglets born after kisspeptin‑10 was not different from that after GnRH.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changePiglets born alive
    Study

    pign = 198

    weaned sows in a fixed-time artificial insemination programme
    Comparator
    GnRH (gonadorelin) group
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.5 or 1 mgAs given in this study (pig).

    Source sentences

    Summary
    Moreover, the total numbers of piglets born and those born alive did not differ among the three groups.
    2 context sentences
    Summary · context
    One hundred ninety-eight weaned sows were divided into three groups at random.
    Summary · context
    A FTAI-GnRH group of sows (n = 98) received 100 µg (2 mL) gonadotropin-releasing hormone (GnRH; gonadorelin) by intramuscular injection at 96 h after weaning (t = 0 h); FTAI-KPL (KPL: low-dose KP-10, n = 50), and FTAI-KPH groups of sows (KPH: high-dose KP-10, n = 50) received 0.5 or 1 mg KP-10 (2 mL…
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In weaned sows, oestrus rates after 0.5 mg or 1 mg kisspeptin‑10 did not differ from the GnRH group.

    In plain wordsIn sows, oestrus rates after kisspeptin‑10 were not different from those after GnRH.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeOestrus rate
    Study

    pign: not reported in source

    weaned sows in a fixed-time artificial insemination programme
    Comparator
    GnRH (gonadorelin) group
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.5 or 1 mgAs given in this study (pig).

    Source sentences

    Summary
    The oestrus rates (96 vs 92%; 96 vs 88%) and weaning-to-oestrus intervals (98.9 vs 98.6 h; 98.9 vs 97.1 h) were not affected by treatment
    2 context sentences
    Summary · context
    One hundred ninety-eight weaned sows were divided into three groups at random.
    Summary · context
    A FTAI-GnRH group of sows (n = 98) received 100 µg (2 mL) gonadotropin-releasing hormone (GnRH; gonadorelin) by intramuscular injection at 96 h after weaning (t = 0 h); FTAI-KPL (KPL: low-dose KP-10, n = 50), and FTAI-KPH groups of sows (KPH: high-dose KP-10, n = 50) received 0.5 or 1 mg KP-10 (2 mL…
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In weaned sows, the weaning-to-oestrus interval after kisspeptin‑10 did not differ from the GnRH group.

    In plain wordsIn sows, the time from weaning to oestrus after kisspeptin‑10 was not different from that after GnRH.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeWeaning-to-oestrus interval
    Study

    pign: not reported in source

    weaned sows in a fixed-time artificial insemination programme
    Comparator
    GnRH (gonadorelin) group
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.5 or 1 mgAs given in this study (pig).

    Source sentences

    Summary
    The oestrus rates (96 vs 92%; 96 vs 88%) and weaning-to-oestrus intervals (98.9 vs 98.6 h; 98.9 vs 97.1 h) were not affected by treatment
    2 context sentences
    Summary · context
    One hundred ninety-eight weaned sows were divided into three groups at random.
    Summary · context
    A FTAI-GnRH group of sows (n = 98) received 100 µg (2 mL) gonadotropin-releasing hormone (GnRH; gonadorelin) by intramuscular injection at 96 h after weaning (t = 0 h); FTAI-KPL (KPL: low-dose KP-10, n = 50), and FTAI-KPH groups of sows (KPH: high-dose KP-10, n = 50) received 0.5 or 1 mg KP-10 (2 mL…
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In weaned sows, oestrus lasted longer with 0.5 mg kisspeptin‑10 than with GnRH (38.7 vs 30.0 h).

    In plain wordsIn sows, oestrus lasted longer after low-dose kisspeptin‑10 than after GnRH.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseDuration of oestrus
    Study

    pign: not reported in source

    weaned sows in a fixed-time artificial insemination programme
    Comparator
    GnRH (gonadorelin) group
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.5 mgAs given in this study (pig).

    Measurements

    Oestrus duration
    38.7 h
    FTAI-KPL
    Oestrus duration
    30 h
    FTAI-GnRH

    Source sentences

    Summary
    oestrus in the FTAI-KPL group was significantly longer than in the FTAI-GnRH group (38.7 vs 30.0 h; P < 0.05
    2 context sentences
    Summary · context
    One hundred ninety-eight weaned sows were divided into three groups at random.
    Summary · context
    A FTAI-GnRH group of sows (n = 98) received 100 µg (2 mL) gonadotropin-releasing hormone (GnRH; gonadorelin) by intramuscular injection at 96 h after weaning (t = 0 h); FTAI-KPL (KPL: low-dose KP-10, n = 50), and FTAI-KPH groups of sows (KPH: high-dose KP-10, n = 50) received 0.5 or 1 mg KP-10 (2 mL…
  6. 06AnimalAnimal study (in vivo)Efficacy outcome

    In weaned sows, peak LH after 0.5 mg kisspeptin‑10 was 1.45 times the baseline value.

    In plain wordsIn sows, low-dose kisspeptin‑10 raised peak LH to 1.45 times the starting level.

    Peptide
    Kisspeptin-10
    Outcome
    IncreasePeak LH concentration relative to baseline, low dose
    Study

    pign: not reported in source

    weaned sows in a fixed-time artificial insemination programme
    Comparator
    Baseline (t0)
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    0.5 mgAs given in this study (pig).

    Measurements

    Peak LH relative to t0
    1.45 fold
    FTAI-KPL

    Source sentences

    Summary
    The peak LH concentrations were 1.29 times greater than at t0 = 0 in the FTAI-GnRH group, and 1.45 and 1.44 times greater than at t0 = 0 in the FTAI-KPL and FTAI-KPH groups, respectively.
    2 context sentences
    Summary · context
    One hundred ninety-eight weaned sows were divided into three groups at random.
    Summary · context
    A FTAI-GnRH group of sows (n = 98) received 100 µg (2 mL) gonadotropin-releasing hormone (GnRH; gonadorelin) by intramuscular injection at 96 h after weaning (t = 0 h); FTAI-KPL (KPL: low-dose KP-10, n = 50), and FTAI-KPH groups of sows (KPH: high-dose KP-10, n = 50) received 0.5 or 1 mg KP-10 (2 mL…
  7. 07AnimalAnimal study (in vivo)Efficacy outcome

    In weaned sows, peak LH after 1 mg kisspeptin‑10 was 1.44 times the baseline value.

    In plain wordsIn sows, high-dose kisspeptin‑10 raised peak LH to 1.44 times the starting level.

    Peptide
    Kisspeptin-10
    Outcome
    IncreasePeak LH concentration relative to baseline, high dose
    Study

    pign: not reported in source

    weaned sows in a fixed-time artificial insemination programme
    Comparator
    Baseline (t0)
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    1 mgAs given in this study (pig).

    Measurements

    Peak LH relative to t0
    1.44 fold
    FTAI-KPH

    Source sentences

    Summary
    The peak LH concentrations were 1.29 times greater than at t0 = 0 in the FTAI-GnRH group, and 1.45 and 1.44 times greater than at t0 = 0 in the FTAI-KPL and FTAI-KPH groups, respectively.
    2 context sentences
    Summary · context
    One hundred ninety-eight weaned sows were divided into three groups at random.
    Summary · context
    A FTAI-GnRH group of sows (n = 98) received 100 µg (2 mL) gonadotropin-releasing hormone (GnRH; gonadorelin) by intramuscular injection at 96 h after weaning (t = 0 h); FTAI-KPL (KPL: low-dose KP-10, n = 50), and FTAI-KPH groups of sows (KPH: high-dose KP-10, n = 50) received 0.5 or 1 mg KP-10 (2 mL…
  8. 08AnimalAnimal study (in vivo)Efficacy outcome

    In weaned sows, follicular diameter did not differ between kisspeptin‑10 and GnRH treatments.

    In plain wordsIn sows, follicle size after kisspeptin‑10 was not different from that after GnRH.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeFollicular diameter
    Study

    pign: not reported in source

    weaned sows in a fixed-time artificial insemination programme
    Comparator
    GnRH (gonadorelin) group
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.5 or 1 mgAs given in this study (pig).

    Source sentences

    Summary
    Follicular diameters and pregnancy rates (86 vs 88%, 86 vs 80%, respectively) did not differ between the treatments.
    2 context sentences
    Summary · context
    One hundred ninety-eight weaned sows were divided into three groups at random.
    Summary · context
    A FTAI-GnRH group of sows (n = 98) received 100 µg (2 mL) gonadotropin-releasing hormone (GnRH; gonadorelin) by intramuscular injection at 96 h after weaning (t = 0 h); FTAI-KPL (KPL: low-dose KP-10, n = 50), and FTAI-KPH groups of sows (KPH: high-dose KP-10, n = 50) received 0.5 or 1 mg KP-10 (2 mL…
  9. 09AnimalAnimal study (in vivo)Efficacy outcome

    In weaned sows, pregnancy rates did not differ between kisspeptin‑10 and GnRH treatments (86 vs 88%, 86 vs 80%).

    In plain wordsIn sows, pregnancy rates after kisspeptin‑10 were not different from those after GnRH.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changePregnancy rate
    Study

    pign: not reported in source

    weaned sows in a fixed-time artificial insemination programme
    Comparator
    GnRH (gonadorelin) group
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.5 or 1 mgAs given in this study (pig).

    Source sentences

    Summary
    Follicular diameters and pregnancy rates (86 vs 88%, 86 vs 80%, respectively) did not differ between the treatments.
    2 context sentences
    Summary · context
    One hundred ninety-eight weaned sows were divided into three groups at random.
    Summary · context
    A FTAI-GnRH group of sows (n = 98) received 100 µg (2 mL) gonadotropin-releasing hormone (GnRH; gonadorelin) by intramuscular injection at 96 h after weaning (t = 0 h); FTAI-KPL (KPL: low-dose KP-10, n = 50), and FTAI-KPH groups of sows (KPH: high-dose KP-10, n = 50) received 0.5 or 1 mg KP-10 (2 mL…

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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