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Study · Measured the body's own peptide · 2021

2 results

Thymosin β4 and β10 are highly expressed at the deep infiltrative margins of colorectal cancer - A mass spectrometry analysis.

Olianas A, Serrao S, Piras V, Manconi B, Contini C, Iavarone F, Pichiri G, Coni P, Zorcolo L, Orrù G, Messana I, Faa G, Castagnola M, Fanni D, Cabras T

European review for medical and pharmacological sciences1 Dec 2021Cited by 3 (Europe PMC)

PMID34919228 (opens in a new tab)DOI10.26355/eurrev_202112_27422 (opens in a new tab)PepBankPUB-34919228
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In tissue from 18 patients with colorectal cancer, Tβ4 levels were higher in the deep part of the tumor than in other zones.

    In plain wordsIn people with colorectal cancer, the body's own Tβ4 was higher in the deep part of the tumor.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseTβ4 level by tumor zone
    Study

    n = 18

    Outcome group
    Endogenous peptide levels · Cancer

    Source sentences

    Summary
    Both Tβ4 and Tβ10, exhibited intra-tumoral quantitative differences, being upregulated in the deep part of the CRC.
    1 context sentence
    Summary · context
    Tβ4 and Tβ10 were analyzed in deep and superficial tumor samples, and normal mucosa from 18 patients.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In colorectal cancer tissue, Tβ4 was more concentrated in patients at Dukes stage B and with budding index 2.

    In plain wordsIn colorectal cancer tissue, the body's own Tβ4 was more concentrated in patients at Dukes stage B and with budding index 2.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseTβ4 level by Dukes stage and budding index
    Study

    n = 18

    Outcome group
    Endogenous peptide levels · Cancer

    Source sentences

    Summary
    They exhibited, moreover, strong association with the Dukes stage and the budding grade, being more concentrated in patients at Dukes stage B and with budding index "2".
    1 context sentence
    Summary · context
    Tβ4 and Tβ10 were analyzed in deep and superficial tumor samples, and normal mucosa from 18 patients.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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