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Study · Observational study · n = 73 · 2021

6 results

Optimizing pediatric histrelin implantation to improve success rates in clinic without sedation.

Krishna V, Lee SL, DeUgarte DA

Journal of pediatric endocrinology & metabolism : JPEM18 Aug 2021Cited by 2 (Europe PMC)

PMID34407329 (opens in a new tab)DOI10.1515/jpem-2021-0432 (opens in a new tab)PepBankPUB-34407329
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. 6 results from people.

  1. 01HumanObservational studySafety outcome

    In pediatric histrelin procedures, implant fracture or counter-incision occurred in 10 procedures (5%).

    In plain wordsIn pediatric histrelin procedures, implant fracture or an additional incision occurred in 10 procedures (5%).

    Peptide
    Histrelin
    Outcome
    Not applicableProcedural complications
    Study

    n = 73

    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated

    Measurements

    Procedures with complications
    10 procedures
    histrelin implant procedures (fracture or counter-incision)
    Complication rate
    5%
    histrelin implant procedures

    Source sentences

    Summary
    Complications (i.e. implant fracture or need for counter-incision) were noted in 10 of the procedures (5%).
    1 context sentence
    Summary · context
    A retrospective study was performed for histrelin implant procedures done at our institution from 2008 to 2020.
  2. 02HumanObservational studySafety outcome

    In pediatric histrelin procedures, dermatitis occurred in 1 patient.

    In plain wordsIn pediatric histrelin procedures, dermatitis occurred in 1 patient.

    Peptide
    Histrelin
    Outcome
    Not applicableDermatitis
    Study

    n = 73

    Outcome group
    Adverse events · Skin and wound
    Studied dose
    Dose not stated

    Measurements

    Patients with dermatitis
    1 patients
    histrelin implant procedures

    Source sentences

    Summary
    The only documented wound problem reported was dermatitis in 1 patient (no suture granuloma, dehiscence, or implant extravasation).
    1 context sentence
    Summary · context
    A retrospective study was performed for histrelin implant procedures done at our institution from 2008 to 2020.
  3. 03HumanObservational studySafety outcome

    In pediatric histrelin procedures, no suture granuloma was documented.

    In plain wordsIn pediatric histrelin procedures, no suture granuloma was documented.

    Peptide
    Histrelin
    Outcome
    Not applicableSuture granuloma
    Study

    n = 73

    Outcome group
    Adverse events · Skin and wound
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The only documented wound problem reported was dermatitis in 1 patient (no suture granuloma, dehiscence, or implant extravasation).
    1 context sentence
    Summary · context
    A retrospective study was performed for histrelin implant procedures done at our institution from 2008 to 2020.
  4. 04HumanObservational studySafety outcome

    In pediatric histrelin procedures, no wound dehiscence was documented.

    In plain wordsIn pediatric histrelin procedures, no wound reopening was documented.

    Peptide
    Histrelin
    Outcome
    Not applicableWound dehiscence
    Study

    n = 73

    Outcome group
    Adverse events · Skin and wound
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The only documented wound problem reported was dermatitis in 1 patient (no suture granuloma, dehiscence, or implant extravasation).
    1 context sentence
    Summary · context
    A retrospective study was performed for histrelin implant procedures done at our institution from 2008 to 2020.
  5. 05HumanObservational studySafety outcome

    In pediatric histrelin procedures, no implant extravasation was documented.

    In plain wordsIn pediatric histrelin procedures, no implant extravasation was documented.

    Peptide
    Histrelin
    Outcome
    Not applicableImplant extravasation
    Study

    n = 73

    Outcome group
    Adverse events · Skin and wound
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The only documented wound problem reported was dermatitis in 1 patient (no suture granuloma, dehiscence, or implant extravasation).
    1 context sentence
    Summary · context
    A retrospective study was performed for histrelin implant procedures done at our institution from 2008 to 2020.
  6. 06HumanObservational studySafety outcome

    In pediatric histrelin removal/replacement, complications were associated with longer insertion intervals (21 versus 13 months, p<0.01).

    In plain wordsIn pediatric histrelin removal/replacement, complications were linked to longer insertion intervals than procedures without complications.

    Peptide
    Histrelin
    Outcome
    Not applicableDuration and procedural complication
    Study

    n: not reported in source

    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated

    Measurements

    Interval time from insertion, first reported value
    21 months
    removal/replacement procedures, 21 vs. 13 as reported
    Interval time from insertion, second reported value
    13 months
    removal/replacement procedures, 21 vs. 13 as reported

    Source sentences

    Summary
    The only risk factor identified for a procedural complication during implant removal/replacement was interval time from insertion (21 vs. 13 months; p<0.01).
    1 context sentence
    Summary · context
    A retrospective study was performed for histrelin implant procedures done at our institution from 2008 to 2020.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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