In adults with impaired glucose tolerance or recent type 2 diabetes, month 12 glycemic worsening was less with liraglutide plus metformin than with placebo (hazard ratio 0.21).
In plain wordsIn adults with early blood sugar problems, liraglutide plus metformin led to less worsening of blood sugar control than placebo at 12 months.
- Peptide
- Liraglutide
- Outcome
- DecreaseGlycemic worsening at month 12 in adults
- Study
n: not reported in source
- Comparator
- Placebo
- Outcome group
- Glycemic control · Metabolic and weight
Measurements
- hazard ratio
- 0.21 ratio
- LIRA+MET vs placebo
Source sentences
In adults, month 12 glycemic worsening was less on LIRA+MET versus placebo (hazard ratio 0.21, 95% CI 0.05-0.96, P = 0.044).
1 context sentence(design, population, supporting numbers)
A total of 91 youth (10-19 years) were randomized 1:1 to 12 months of metformin (MET) or 3 months of glargine, followed by 9 months of metformin (G-MET), and 267 adults were randomized to MET, G-MET, liraglutide plus MET (LIRA+MET), or placebo for 12 months.
In this study, Liraglutide was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Liraglutide.