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Study · Randomized controlled trial · n = 893 · 2021

5 results

Single-dose administration of a short-acting gonadotropin-releasing hormone agonist does not affect cycle outcome in frozen-thawed embryo transfer cycles.

Wang H, Tang X, Bukulmez O, Deng C, Yu Q, Zhou Y, Sun Z, Zhen J, Wang X, Liu M

The Journal of international medical research1 May 2021Cited by 2 (Europe PMC)

PMID33947255 (opens in a new tab)PMCIDPMC8113920 (opens in a new tab)DOI10.1177/03000605211012247 (opens in a new tab)PepBankPUB-33947255
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. 5 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In frozen-thawed embryo transfer cycles, adding triptorelin did not significantly change clinical pregnancy rates versus luteal support alone.

    In plain wordsAdding triptorelin did not significantly change clinical pregnancy rates compared with luteal support alone during frozen-thawed embryo transfer.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeClinical pregnancy rate
    Study

    n = 893

    Comparator
    routine luteal support alone
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.1 mgAs given in this study (human).

    Measurements

    Clinical pregnancy rate
    56.3%
    triptorelin group
    Clinical pregnancy rate
    50.58%
    luteal support alone

    Source sentences

    Summary
    In the experimental and control groups, the clinical pregnancy rate was 56.3% and 50.58%, the biochemical pregnancy rate was 15.78% and 18.94%, and the median implantation rate was 39.98% and 38.01%, respectively, with no significant difference between the groups.
    3 context sentences
    Summary · context
    Patients in the experimental group (n = 460) received triptorelin acetate on the day of embryo transfer along with routine luteal support.
    Summary · context
    Patients in the control group (n = 433) only received luteal support.
    Summary · context
    One dose (0.1 mg) of a short-acting GnRHa was administered on the day of blastocyte transfer.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In frozen-thawed embryo transfer cycles, adding triptorelin did not significantly change biochemical pregnancy rates versus luteal support alone.

    In plain wordsAdding triptorelin did not significantly change biochemical pregnancy rates compared with luteal support alone during frozen-thawed embryo transfer.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeBiochemical pregnancy rate
    Study

    n = 893

    Comparator
    routine luteal support alone
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.1 mgAs given in this study (human).

    Measurements

    Biochemical pregnancy rate
    15.78%
    triptorelin group
    Biochemical pregnancy rate
    18.94%
    luteal support alone

    Source sentences

    Summary
    In the experimental and control groups, the clinical pregnancy rate was 56.3% and 50.58%, the biochemical pregnancy rate was 15.78% and 18.94%, and the median implantation rate was 39.98% and 38.01%, respectively, with no significant difference between the groups.
    3 context sentences
    Summary · context
    Patients in the experimental group (n = 460) received triptorelin acetate on the day of embryo transfer along with routine luteal support.
    Summary · context
    Patients in the control group (n = 433) only received luteal support.
    Summary · context
    One dose (0.1 mg) of a short-acting GnRHa was administered on the day of blastocyte transfer.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In frozen-thawed embryo transfer cycles, adding triptorelin did not significantly change implantation rates versus luteal support alone.

    In plain wordsAdding triptorelin did not significantly change implantation rates compared with luteal support alone during frozen-thawed embryo transfer.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeImplantation rate
    Study

    n = 893

    Comparator
    routine luteal support alone
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.1 mgAs given in this study (human).

    Measurements

    Median implantation rate
    39.98%
    triptorelin group
    Median implantation rate
    38.01%
    luteal support alone

    Source sentences

    Summary
    In the experimental and control groups, the clinical pregnancy rate was 56.3% and 50.58%, the biochemical pregnancy rate was 15.78% and 18.94%, and the median implantation rate was 39.98% and 38.01%, respectively, with no significant difference between the groups.
    3 context sentences
    Summary · context
    Patients in the experimental group (n = 460) received triptorelin acetate on the day of embryo transfer along with routine luteal support.
    Summary · context
    Patients in the control group (n = 433) only received luteal support.
    Summary · context
    One dose (0.1 mg) of a short-acting GnRHa was administered on the day of blastocyte transfer.
  4. 04HumanRandomized controlled trialSafety outcome

    In frozen-thawed embryo transfer cycles, adding triptorelin did not significantly change abortion rates versus luteal support alone.

    In plain wordsAdding triptorelin did not significantly change pregnancy loss rates compared with luteal support alone during frozen-thawed embryo transfer.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeAbortion rate
    Study

    n = 893

    Comparator
    routine luteal support alone
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.1 mgAs given in this study (human).

    Source sentences

    Summary
    Biochemical pregnancy and abortion and the ectopic pregnancy rate were not significantly different between the two groups.
    3 context sentences
    Summary · context
    Patients in the experimental group (n = 460) received triptorelin acetate on the day of embryo transfer along with routine luteal support.
    Summary · context
    Patients in the control group (n = 433) only received luteal support.
    Summary · context
    One dose (0.1 mg) of a short-acting GnRHa was administered on the day of blastocyte transfer.
  5. 05HumanRandomized controlled trialSafety outcome

    In frozen-thawed embryo transfer cycles, adding triptorelin did not significantly change ectopic pregnancy rates versus luteal support alone.

    In plain wordsAdding triptorelin did not significantly change ectopic pregnancy rates compared with luteal support alone during frozen-thawed embryo transfer.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeEctopic pregnancy rate
    Study

    n = 893

    Comparator
    routine luteal support alone
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.1 mgAs given in this study (human).

    Source sentences

    Summary
    Biochemical pregnancy and abortion and the ectopic pregnancy rate were not significantly different between the two groups.
    3 context sentences
    Summary · context
    Patients in the experimental group (n = 460) received triptorelin acetate on the day of embryo transfer along with routine luteal support.
    Summary · context
    Patients in the control group (n = 433) only received luteal support.
    Summary · context
    One dose (0.1 mg) of a short-acting GnRHa was administered on the day of blastocyte transfer.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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