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Study · In vitro (cells) · rat · 2021

3 results

Kisspeptin leads to calcium signaling in cultured rat dorsal root ganglion neurons.

Kelestimur H, Bulut F, Canpolat S, Ozcan M, Ayar A

General physiology and biophysics1 Mar 2021Cited by 1 (Europe PMC)

PMID33881002 (opens in a new tab)DOI10.4149/gpb_2020047 (opens in a new tab)PepBankPUB-33881002
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In cultured rat dorsal root ganglion neurons, bath application of kisspeptin‑10 increased intracellular free calcium levels.

    In plain wordsIn rat nerve cells in the lab, kisspeptin‑10 raised calcium levels inside the cells.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseIntracellular free calcium ([Ca2+]i)
    Study

    ratn: not reported in source

    Cultured rat dorsal root ganglion (DRG) neurons
    Outcome group
    Pain · Nervous system and cognition
    Studied dose
    Dose not stated · bath applicationAs given in this study (rat).

    Source sentences

    Summary
    Bath application of kisspeptin-10 increased intracellular free calcium levels ([Ca2+]i).
  2. 02LabIn vitro (cells)Mechanism

    In cultured rat DRG neurons without extracellular calcium, kisspeptin induced an attenuated but still significant increase in [Ca2+]i.

    In plain wordsIn rat nerve cells in the lab, kisspeptin still raised internal calcium without outside calcium, but less strongly.

    Peptide
    Kisspeptin-10
    Outcome
    Increase[Ca2+]i without extracellular calcium
    Study

    ratn: not reported in source

    Cultured rat dorsal root ganglion (DRG) neurons
    Outcome group
    Pain · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In the absence of extracellular calcium, the kisspeptin induced an attenuated but still significant increase in [Ca2+]i.
  3. 03LabIn vitro (cells)Mechanism

    In cultured rat DRG neurons, kisspeptin‑10 still increased [Ca2+]i in the presence of a PKC inhibitor.

    In plain wordsIn rat nerve cells in the lab, the calcium response to kisspeptin continued when PKC was blocked.

    Peptide
    Kisspeptin-10
    Outcome
    Increase[Ca2+]i with PKC inhibitor
    Study

    ratn: not reported in source

    Cultured rat dorsal root ganglion (DRG) neurons
    Outcome group
    Pain · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    [Ca2+]i responses persisted in the presence of protein kinase C (PKC) inhibitor.
    1 context sentence
    Summary · context
    Bath application of kisspeptin-10

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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