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Study · Measured the body's own peptide · 2021

3 results

Changes in serum adipokines during natural extended fasts in female northern elephant seals.

Rzucidlo CL, Sperou ES, Holser RR, Khudyakov JI, Costa DP, Crocker DE

General and comparative endocrinology27 Mar 2021Cited by 3 (Europe PMC)

PMID33781740 (opens in a new tab)DOI10.1016/j.ygcen.2021.113760 (opens in a new tab)PepBankPUB-33781740
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In female northern elephant seals, natural circulating kisspeptin‑54 concentrations were highest at the end of the breeding haul-out.

    In plain wordsIn female northern elephant seals, the body's own kisspeptin‑54 levels were highest at the end of the breeding haul-out.

    Peptide
    Kisspeptin-54 (metastin)
    Outcome
    MixedCirculating kisspeptin-54 by life-history stage
    Study

    northern elephant sealn = 196

    Wild female seals during natural fasts
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    Kisspeptin-54 concentrations were highest at the end of the breeding haul-out.
    1 context sentence
    Summary · context
    We measured circulating levels of four adipokines: leptin, resistin, adiponectin, and kisspeptin-54, in 196 serum samples from female NES at the beginning and end of their breeding and molting fasts.

    This result measures the body's own Kisspeptin-54 (metastin). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In female northern elephant seals, natural kisspeptin‑54 concentrations were associated with cortisol, and higher cortisol late in lactation went with higher kisspeptin‑54.

    In plain wordsIn female northern elephant seals, the body's own kisspeptin‑54 levels were linked to cortisol and rose with higher cortisol late in lactation.

    Peptide
    Kisspeptin-54 (metastin)
    Outcome
    IncreaseAssociation of kisspeptin-54 with cortisol
    Study

    northern elephant sealn = 196

    Wild female seals during natural fasts
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    Increased cortisol concentrations late in lactation were associated with increased kisspeptin-54, suggesting a link to ovulation initiation in NES.
    2 context sentences
    Summary · context
    Resistin, adiponectin, and kisspeptin-54 were associated with circulating cortisol concentrations.
    Summary · context
    We measured circulating levels of four adipokines: leptin, resistin, adiponectin, and kisspeptin-54, in 196 serum samples from female NES at the beginning and end of their breeding and molting fasts.

    This result measures the body's own Kisspeptin-54 (metastin). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In female northern elephant seals, natural kisspeptin‑54 concentrations showed no relationship with leptin.

    In plain wordsIn female northern elephant seals, the body's own kisspeptin‑54 levels were not linked to leptin levels.

    Peptide
    Kisspeptin-54 (metastin)
    Outcome
    No significant changeAssociation of kisspeptin-54 with leptin
    Study

    northern elephant sealn = 196

    Wild female seals during natural fasts
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    the lack of a relationship between leptin and kisspeptin-54
    1 context sentence
    Summary · context
    We measured circulating levels of four adipokines: leptin, resistin, adiponectin, and kisspeptin-54, in 196 serum samples from female NES at the beginning and end of their breeding and molting fasts.

    This result measures the body's own Kisspeptin-54 (metastin). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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