In wild-type male mice, pegvisomant impaired restraint stress-induced prolactin release.
In plain wordsIn male mice, pegvisomant reduced prolactin release during restraint stress.
- Peptide
- Pegvisomant
- Outcome
- DecreaseStress-induced prolactin release
- Study
mousen: not reported in source
Wild-type male mice under restraint stress- Outcome group
- Endogenous peptide levels · Endocrine and hormones
- Studied dose
- Dose not stated
Source sentences
However, restraint stress-induced prolactin release was significantly impaired in DAT- and TH-specific GHR knockout male mice, as well as in pegvisomant-treated wild-type males, whereas an intact response was observed in females.