Effects of Kiss2 on the Expression of Gonadotropin Genes in the Pituitary of Nile Tilapia (Oreochromis niloticus).

Park JW, Kim JH, Kwon JY

Development & reproduction30 Sept 2020Cited by 4 (Europe PMC)

PMID33110946PMCIDPMC7576967DOI10.12717/dr.2020.24.3.149PepBankPUB-33110946

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

4 results from studies that gave the peptide. No result from this study comes from people.

01LabEx vivo tissueMechanism
In cultured Nile tilapia pituitaries, Kp-10 at more than 0.1 μM for 3 hours increased fshβ mRNA expression.
In plain wordsIn lab-cultured fish pituitary tissue, high concentrations of kisspeptin‑10 raised the activity of the FSH gene after 3 hours.
Peptide
Kisspeptin-10
Outcome
Increasefshβ mRNA after 3 h of high-concentration Kp-10
Study
Nile tilapian: not reported in source
Cultured pituitary tissue
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
more than 0.1 μM · 3 hoursAs given in this study (Nile tilapia).
Source sentences
Summary
Pituitaries cultured with high concentration of Kp-10 more than 0.1 μM for 3 hours exhibited a significant increase of fshβ mRNA expression, but not lhβ mRNA.
1 context sentence(design, population, supporting numbers)
Summary · context
In the present study, pituitaries of the Nile tilapia (Oreochromis niloticus) were cultured at different concentrations of kisspeptin-10 (Kp-10, FNYNPLSLRF) for 3 hours to observe the effect of kisspeptin on the expression of follicle-stimulating hormone β subunit (fshβ) gene and lutei…
Report a problemFND-3311094601
02LabEx vivo tissueMechanism
In cultured Nile tilapia pituitaries, Kp-10 at more than 0.1 μM for 3 hours did not increase lhβ mRNA expression.
In plain wordsIn lab-cultured fish pituitary tissue, high concentrations of kisspeptin‑10 did not raise the activity of the LH gene after 3 hours.
Peptide
Kisspeptin-10
Outcome
No significant changelhβ mRNA after 3 h of high-concentration Kp-10
Study
Nile tilapian: not reported in source
Cultured pituitary tissue
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
more than 0.1 μM · 3 hoursAs given in this study (Nile tilapia).
Source sentences
Summary
Pituitaries cultured with high concentration of Kp-10 more than 0.1 μM for 3 hours exhibited a significant increase of fshβ mRNA expression, but not lhβ mRNA.
1 context sentence(design, population, supporting numbers)
Summary · context
In the present study, pituitaries of the Nile tilapia (Oreochromis niloticus) were cultured at different concentrations of kisspeptin-10 (Kp-10, FNYNPLSLRF) for 3 hours to observe the effect of kisspeptin on the expression of follicle-stimulating hormone β subunit (fshβ) gene and lutei…
Report a problemFND-3311094602
03LabEx vivo tissueMechanism
In cultured Nile tilapia pituitaries, 0.1 μM Kp-10 increased fshβ mRNA after 6 hours compared with control medium.
In plain wordsIn lab-cultured fish pituitary tissue, kisspeptin‑10 raised the activity of the FSH gene after 6 hours compared with control.
Peptide
Kisspeptin-10
Outcome
Increasefshβ mRNA after 6 h of 0.1 μM Kp-10
Study
Nile tilapian: not reported in source
Cultured pituitary tissue
Comparator
Control medium
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
0.1 μM · 6 hoursAs given in this study (Nile tilapia).
Source sentences
Summary
The expression of both fshβ and lhβ mRNA increased after 6 hours in 0.1 μM of Kp-10 medium in comparison with that in the control medium.
1 context sentence(design, population, supporting numbers)
Summary · context
Pituitary tissues were cultured with 0.1 μM of Kp-10, luteinizing hormone releasing hormone (LHRH), or LHRH+Kp-10 for 3, 6, 12, and 24 hours to investigate changes in the expression of fshβ and lhβ mRNA.
Report a problemFND-3311094603
04LabEx vivo tissueMechanism
In cultured Nile tilapia pituitaries, 0.1 μM Kp-10 increased lhβ mRNA after 6 hours compared with control medium.
In plain wordsIn lab-cultured fish pituitary tissue, kisspeptin‑10 raised the activity of the LH gene after 6 hours compared with control.
Peptide
Kisspeptin-10
Outcome
Increaselhβ mRNA after 6 h of 0.1 μM Kp-10
Study
Nile tilapian: not reported in source
Cultured pituitary tissue
Comparator
Control medium
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
0.1 μM · 6 hoursAs given in this study (Nile tilapia).
Source sentences
Summary
The expression of both fshβ and lhβ mRNA increased after 6 hours in 0.1 μM of Kp-10 medium in comparison with that in the control medium.
1 context sentence(design, population, supporting numbers)
Summary · context
Pituitary tissues were cultured with 0.1 μM of Kp-10, luteinizing hormone releasing hormone (LHRH), or LHRH+Kp-10 for 3, 6, 12, and 24 hours to investigate changes in the expression of fshβ and lhβ mRNA.
Report a problemFND-3311094604

Studies that did not test the peptide alone2

In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Kisspeptin-10.

05LabNot a test of Kisspeptin-10 aloneEx vivo tissueMechanism
In cultured Nile tilapia pituitaries, LHRH plus Kp-10 did not change fshβ mRNA compared with control.
In plain wordsIn lab-cultured fish pituitary tissue, LHRH and kisspeptin‑10 together did not change the activity of the FSH gene compared with control.
Peptide
Kisspeptin-10
Outcome
No significant changefshβ mRNA with LHRH plus Kp-10
Study
Nile tilapian: not reported in source
Cultured pituitary tissue
Comparator
Control medium
Outcome group
Sex hormones and fertility · Endocrine and hormones
Source sentences
Summary
There were no significant differences of fshβ and lhβ gene expression in tissues cultured with LHRH+KP-10 medium compared with the control.
1 context sentence(design, population, supporting numbers)
Summary · context
Pituitary tissues were cultured with 0.1 μM of Kp-10, luteinizing hormone releasing hormone (LHRH), or LHRH+Kp-10 for 3, 6, 12, and 24 hours to investigate changes in the expression of fshβ and lhβ mRNA.
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.
Report a problemFND-3311094605
06LabNot a test of Kisspeptin-10 aloneEx vivo tissueMechanism
In cultured Nile tilapia pituitaries, LHRH plus Kp-10 did not change lhβ mRNA compared with control.
In plain wordsIn lab-cultured fish pituitary tissue, LHRH and kisspeptin‑10 together did not change the activity of the LH gene compared with control.
Peptide
Kisspeptin-10
Outcome
No significant changelhβ mRNA with LHRH plus Kp-10
Study
Nile tilapian: not reported in source
Cultured pituitary tissue
Comparator
Control medium
Outcome group
Sex hormones and fertility · Endocrine and hormones
Source sentences
Summary
There were no significant differences of fshβ and lhβ gene expression in tissues cultured with LHRH+KP-10 medium compared with the control.
1 context sentence(design, population, supporting numbers)
Summary · context
Pituitary tissues were cultured with 0.1 μM of Kp-10, luteinizing hormone releasing hormone (LHRH), or LHRH+Kp-10 for 3, 6, 12, and 24 hours to investigate changes in the expression of fshβ and lhβ mRNA.
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.
Report a problemFND-3311094606

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
10 Oct 2026, 09:43 UTC
Study results updated
Version 1
9 Oct 2026, 03:04 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

Keywords

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