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Study · Not a test of the peptide alone · 2021

4 results

Acute carnosine and β-alanine supplementation increase the compensated part of the ventilation versus work rate relationship during a ramp incremental cycle test in physically active men.

Limonta E, Invernizzi PL, Rampichini S, Bisconti AV, Cè E, Longo S, Coratella G, Iaia FM, Esposito F

The Journal of sports medicine and physical fitness22 Oct 2020Cited by 2 (Europe PMC)

PMID33092320 (opens in a new tab)DOI10.23736/s0022-4707.20.10887-9 (opens in a new tab)PepBankPUB-33092320
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking L-carnosine.

  1. 01HumanNot a test of L-carnosine aloneRandomized controlled trialEfficacy outcome

    In healthy men, combined L‑carnosine and β-alanine did not differ from placebo in peak exercise parameters.

    In plain wordsIn healthy men, combined L‑carnosine and β-alanine did not change peak exercise parameters compared with placebo.

    Peptide
    L-carnosine
    Outcome
    No significant changePeak exercise parameters
    Study

    n = 10

    Comparator
    Placebo
    Outcome group
    Exercise and physical function · Respiratory

    Source sentences

    Summary
    No differences between the experimental conditions emerged at peak exercise.
    2 context sentences
    Summary · context
    This randomized, double-blind, placebo-controlled study, involved 10 healthy males (age: 22.2±1.9 years, body mass: 72.5±7.9 kg, stature: 1.72±0.08 m, Body Mass Index: 24.47±1.91 kg/m2, mean±standard deviation).
    Summary · context
    All the participants performed two maximal incremental ramp tests on a cycle ergometer, with a prior randomized assumption of 2.5 g L-carnosine plus 2.5 g β-alanine (Carn-βA) or placebo (PLA).

    In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.

  2. 02HumanNot a test of L-carnosine aloneRandomized controlled trialEfficacy outcome

    In healthy men, combined L‑carnosine and β-alanine did not affect the first ventilatory threshold versus placebo.

    In plain wordsIn healthy men, combined L‑carnosine and β-alanine did not affect the first ventilatory threshold compared with placebo.

    Peptide
    L-carnosine
    Outcome
    No significant changeFirst ventilatory threshold
    Study

    n = 10

    Comparator
    Placebo
    Outcome group
    Exercise and physical function · Respiratory

    Source sentences

    Summary
    However, despite acute Carn-ßA supplementation did not affect the single ventilatory thresholds, the compensated portion of the ramp test (i.e. the difference between VT2 and VT1) was significantly larger (P=0.043) in Carn-ßA.
    2 context sentences
    Summary · context
    This randomized, double-blind, placebo-controlled study, involved 10 healthy males (age: 22.2±1.9 years, body mass: 72.5±7.9 kg, stature: 1.72±0.08 m, Body Mass Index: 24.47±1.91 kg/m2, mean±standard deviation).
    Summary · context
    All the participants performed two maximal incremental ramp tests on a cycle ergometer, with a prior randomized assumption of 2.5 g L-carnosine plus 2.5 g β-alanine (Carn-βA) or placebo (PLA).

    In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.

  3. 03HumanNot a test of L-carnosine aloneRandomized controlled trialEfficacy outcome

    In healthy men, combined L‑carnosine and β-alanine did not affect the second ventilatory threshold versus placebo.

    In plain wordsIn healthy men, combined L‑carnosine and β-alanine did not affect the second ventilatory threshold compared with placebo.

    Peptide
    L-carnosine
    Outcome
    No significant changeSecond ventilatory threshold
    Study

    n = 10

    Comparator
    Placebo
    Outcome group
    Exercise and physical function · Respiratory

    Source sentences

    Summary
    However, despite acute Carn-ßA supplementation did not affect the single ventilatory thresholds, the compensated portion of the ramp test (i.e. the difference between VT2 and VT1) was significantly larger (P=0.043) in Carn-ßA.
    2 context sentences
    Summary · context
    This randomized, double-blind, placebo-controlled study, involved 10 healthy males (age: 22.2±1.9 years, body mass: 72.5±7.9 kg, stature: 1.72±0.08 m, Body Mass Index: 24.47±1.91 kg/m2, mean±standard deviation).
    Summary · context
    All the participants performed two maximal incremental ramp tests on a cycle ergometer, with a prior randomized assumption of 2.5 g L-carnosine plus 2.5 g β-alanine (Carn-βA) or placebo (PLA).

    In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.

  4. 04HumanNot a test of L-carnosine aloneRandomized controlled trialEfficacy outcome

    In healthy men, combined L‑carnosine and β-alanine increased the difference between VT2 and VT1 versus placebo (P=0.043).

    In plain wordsIn healthy men, combined L‑carnosine and β-alanine increased the compensated portion of exercise compared with placebo.

    Peptide
    L-carnosine
    Outcome
    IncreaseCompensated portion of ramp test
    Study

    n = 10

    Comparator
    Placebo
    Outcome group
    Exercise and physical function · Respiratory

    Source sentences

    Summary
    However, despite acute Carn-ßA supplementation did not affect the single ventilatory thresholds, the compensated portion of the ramp test (i.e. the difference between VT2 and VT1) was significantly larger (P=0.043) in Carn-ßA.
    2 context sentences
    Summary · context
    This randomized, double-blind, placebo-controlled study, involved 10 healthy males (age: 22.2±1.9 years, body mass: 72.5±7.9 kg, stature: 1.72±0.08 m, Body Mass Index: 24.47±1.91 kg/m2, mean±standard deviation).
    Summary · context
    All the participants performed two maximal incremental ramp tests on a cycle ergometer, with a prior randomized assumption of 2.5 g L-carnosine plus 2.5 g β-alanine (Carn-βA) or placebo (PLA).

    In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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