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Study · Animal study (in vivo) · mouse · 2020

1 result

Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis.

Winther-Sørensen M, Galsgaard KD, Santos A, Trammell SAJ, Sulek K, Kuhre RE, Pedersen J, Andersen DB, Hassing AS, Dall M, Treebak JT, Gillum MP and 15 more

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Torekov SS, Windeløv JA, Hunt JE, Kjeldsen SAS, Jepsen SL, Vasilopoulou CG, Knop FK, Ørskov C, Werge MP, Bisgaard HC, Eriksen PL, Vilstrup H, Gluud LL, Holst JJ, Wewer Albrechtsen NJ

Molecular metabolism13 Sept 2020Cited by 120 (Europe PMC)

PMID32937194 (opens in a new tab)PMCIDPMC7560169 (opens in a new tab)DOI10.1016/j.molmet.2020.101080 (opens in a new tab)PepBankPUB-32937194
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Summary

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Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In mice, glucagon administration increased urea formation within minutes.

    In plain wordsIn mice, glucagon increased urea formation within minutes.

    Peptide
    Glucagon
    Outcome
    IncreaseUrea formation
    Study

    micen: not reported in source

    Outcome group
    Liver fat and liver function · Liver
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Glucagon administration markedly changed the secretion of rat liver metabolites and within minutes increased urea formation in mice, in perfused rat liver, and in primary human hepatocytes.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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