Top down proteomic analysis of gingival crevicular fluid in deciduous, exfoliating and permanent teeth in children.

Iavarone F, Olianas A, Patini R, Gallenzi P, Di Tonno L, Desiderio C, Cabras T, Manconi B, Vincenzoni F, Cordaro M, Messana I, Urbani A, Castagnola M

Journal of proteomics3 Jul 2020Cited by 9 (Europe PMC)

PMID32629195DOI10.1016/j.jprot.2020.103890PepBankPUB-32629195

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01HumanEndogenous levelObservational studyOther
Top-down proteomics confirmed the presence of Thymosin β4 in gingival crevicular fluid of children.
In plain wordsIn children, the body's own Thymosin β4 was found in the fluid of the gum crevice.
Peptide
Thymosin beta-4 (human)
Outcome
Not applicablePresence of Tβ4 in gingival crevicular fluid
Study
n = 20
Outcome group
Endogenous peptide levels · Whole body
Source sentences
Summary
The results obtained confirmed the presence in GCF of α-Defensins 1-4, Thymosin β4 and Thymosin β10, as described in previous works
1 context sentence(design, population, supporting numbers)
Summary · context
Gingival Crevicular Fluid (GCF), a plasma-derived exudate present in the gingival crevice was collected from deciduous, exfoliating and permanent teeth from 20 children (60 samples) with the aim to characterize and quantify by a mass spectrometry based top-down proteomic approach, the peptide/protei…
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-3262919501
02HumanEndogenous levelObservational studyOther
Top-down proteomics found fragments of Thymosin β4 in gingival crevicular fluid of children, not described before.
In plain wordsIn children, pieces of the body's own Thymosin β4 were found in gum crevice fluid, not reported before.
Peptide
Thymosin beta-4 (human)
Outcome
Not applicableTβ4 fragments in gingival crevicular fluid
Study
n = 20
Outcome group
Endogenous peptide levels · Whole body
Source sentences
Summary
fragments of Thymosin β4 and Thymosin β10; Fibrinopeptide A
1 context sentence(design, population, supporting numbers)
Summary · context
Gingival Crevicular Fluid (GCF), a plasma-derived exudate present in the gingival crevice was collected from deciduous, exfoliating and permanent teeth from 20 children (60 samples) with the aim to characterize and quantify by a mass spectrometry based top-down proteomic approach, the peptide/protei…
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-3262919502

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
13 Oct 2026, 01:52 UTC
Study results updated
Version 1
12 Oct 2026, 18:17 UTC
First added · source update from Europe PMC

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