In hepatic stellate cells, the mitochondrial protective agent SS‑31 partially reversed the inhibition of mitochondrial function caused by ligustrazine and/or paeonol.
In plain wordsIn cells, SS‑31 partly offset the loss of mitochondrial function caused by two herbal compounds.
- Peptide
- Elamipretide (SS-31)
- Outcome
- IncreaseHepatic stellate cell mitochondrial function with SS-31 after ligustrazine/paeonol
- Study
n: not reported in source
Hepatic stellate cells (HSC)- Outcome group
- Mitochondrial function · Liver
Source sentences
The inhibitory effects of ligustrazine or/and Paeonol on mitochondrial function is partially balanced by mitochondrial protective agent SS-31.
1 context sentence(design, population, supporting numbers)
Mito-Tacker fluorescence staining and mitochondrial DNA copy number were measured to observe the effect of ligustrazine or/and paeonol on mitochondrial function of hepatic stellate cell (HSC).
In this study, Elamipretide (SS-31) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Elamipretide (SS-31).