Effect of Kisspeptin-54 immunization on performance, carcass characteristics, meat quality and safety of Yiling goats.

Wassie T, Zeng F, Jiang X, Liu G, Kasimu H, Ling S, Girmay S

Meat science7 Apr 2020Cited by 12 (Europe PMC)

PMID32289558DOI10.1016/j.meatsci.2020.108139PepBankPUB-32289558

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study14

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone14

In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Kisspeptin-54 (metastin).

01AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Mechanism
In buck goats, the PBK-asd kisspeptin‑54 DNA vaccine raised serum anti-kisspeptin antibody production versus control.
In plain wordsIn goats, a kisspeptin‑54 DNA vaccine raised anti-kisspeptin antibodies compared with control goats.
Peptide
Kisspeptin-54 (metastin)
Outcome
IncreaseSerum anti-kisspeptin antibody production
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Comparator
Control group
Outcome group
Immune response · Immune and inflammation
Source sentences
Summary
PBK-asd immunization significantly stimulated serum anti-kisspeptin antibody production and reduced testosterone hormone compared with the control group (p < .05).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955801
02AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Efficacy outcome
In buck goats, the PBK-asd kisspeptin‑54 DNA vaccine lowered testosterone versus control.
In plain wordsIn goats, a kisspeptin‑54 DNA vaccine lowered testosterone compared with control goats.
Peptide
Kisspeptin-54 (metastin)
Outcome
DecreaseSerum testosterone
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Comparator
Control group
Outcome group
Sex hormones and fertility · Endocrine and hormones
Source sentences
Summary
PBK-asd immunization significantly stimulated serum anti-kisspeptin antibody production and reduced testosterone hormone compared with the control group (p < .05).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955802
03AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Safety outcome
In buck goats, the PBK-asd plasmid did not integrate into the host genome.
In plain wordsIn goats, the kisspeptin‑54 DNA vaccine plasmid did not integrate into the animals' genome.
Peptide
Kisspeptin-54 (metastin)
Outcome
No significant changePlasmid integration into the host genome
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Outcome group
Adverse events · Whole body
Source sentences
Summary
PBK-asd plasmid did not integrate into the host genome and had no significant effect on growth hormone, body weight, and average daily gain (ADG).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955803
04AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Safety outcome
In buck goats, the PBK-asd kisspeptin‑54 DNA vaccine had no significant effect on growth hormone versus control.
In plain wordsIn goats, a kisspeptin‑54 DNA vaccine did not significantly change growth hormone compared with control goats.
Peptide
Kisspeptin-54 (metastin)
Outcome
No significant changeGrowth hormone
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Comparator
Control group
Outcome group
Growth hormone and IGF-1 · Endocrine and hormones
Source sentences
Summary
Interestingly, PBK-asd plasmid did not integrate into the host genome and had no significant effect on growth hormone, body weight, and average daily gain (ADG).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955804
05AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Safety outcome
In buck goats, the PBK-asd kisspeptin‑54 DNA vaccine had no significant effect on body weight versus control.
In plain wordsIn goats, a kisspeptin‑54 DNA vaccine did not significantly change body weight compared with control goats.
Peptide
Kisspeptin-54 (metastin)
Outcome
No significant changeBody weight
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Comparator
Control group
Outcome group
Body weight · Metabolic and weight
Source sentences
Summary
Interestingly, PBK-asd plasmid did not integrate into the host genome and had no significant effect on growth hormone, body weight, and average daily gain (ADG).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955805
06AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Safety outcome
In buck goats, the PBK-asd kisspeptin‑54 DNA vaccine had no significant effect on average daily gain versus control.
In plain wordsIn goats, a kisspeptin‑54 DNA vaccine did not significantly change daily weight gain compared with control goats.
Peptide
Kisspeptin-54 (metastin)
Outcome
No significant changeAverage daily gain
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Comparator
Control group
Outcome group
Body weight · Metabolic and weight
Source sentences
Summary
Interestingly, PBK-asd plasmid did not integrate into the host genome and had no significant effect on growth hormone, body weight, and average daily gain (ADG).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955806
07AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Safety outcome
In buck goats, the PBK-asd kisspeptin‑54 DNA vaccine did not affect dressing percentage versus control.
In plain wordsIn goats, a kisspeptin‑54 DNA vaccine did not change the carcass dressing percentage compared with control goats.
Peptide
Kisspeptin-54 (metastin)
Outcome
No significant changeDressing percentage
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Comparator
Control group
Outcome group
Body composition · Metabolic and weight
Source sentences
Summary
Furthermore, PBK-asd immunization did not affect carcass characteristics (dressing percentage, loin area, and fat thickness) and meat quality traits (pH, color, cooking loss, drip loss, and shearing force).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955807
08AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Safety outcome
In buck goats, the PBK-asd kisspeptin‑54 DNA vaccine did not affect loin area versus control.
In plain wordsIn goats, a kisspeptin‑54 DNA vaccine did not change loin area compared with control goats.
Peptide
Kisspeptin-54 (metastin)
Outcome
No significant changeLoin area
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Comparator
Control group
Outcome group
Body composition · Metabolic and weight
Source sentences
Summary
Furthermore, PBK-asd immunization did not affect carcass characteristics (dressing percentage, loin area, and fat thickness) and meat quality traits (pH, color, cooking loss, drip loss, and shearing force).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955808
09AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Safety outcome
In buck goats, the PBK-asd kisspeptin‑54 DNA vaccine did not affect fat thickness versus control.
In plain wordsIn goats, a kisspeptin‑54 DNA vaccine did not change fat thickness compared with control goats.
Peptide
Kisspeptin-54 (metastin)
Outcome
No significant changeFat thickness
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Comparator
Control group
Outcome group
Body composition · Metabolic and weight
Source sentences
Summary
Furthermore, PBK-asd immunization did not affect carcass characteristics (dressing percentage, loin area, and fat thickness) and meat quality traits (pH, color, cooking loss, drip loss, and shearing force).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955809
10AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Safety outcome
In buck goats, the PBK-asd kisspeptin‑54 DNA vaccine did not affect meat pH versus control.
In plain wordsIn goats, a kisspeptin‑54 DNA vaccine did not change meat pH compared with control goats.
Peptide
Kisspeptin-54 (metastin)
Outcome
No significant changeMeat pH
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Comparator
Control group
Outcome group
Body composition · Metabolic and weight
Source sentences
Summary
Furthermore, PBK-asd immunization did not affect carcass characteristics (dressing percentage, loin area, and fat thickness) and meat quality traits (pH, color, cooking loss, drip loss, and shearing force).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955810
11AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Safety outcome
In buck goats, the PBK-asd kisspeptin‑54 DNA vaccine did not affect meat color versus control.
In plain wordsIn goats, a kisspeptin‑54 DNA vaccine did not change meat color compared with control goats.
Peptide
Kisspeptin-54 (metastin)
Outcome
No significant changeMeat color
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Comparator
Control group
Outcome group
Body composition · Metabolic and weight
Source sentences
Summary
Furthermore, PBK-asd immunization did not affect carcass characteristics (dressing percentage, loin area, and fat thickness) and meat quality traits (pH, color, cooking loss, drip loss, and shearing force).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955811
12AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Safety outcome
In buck goats, the PBK-asd kisspeptin‑54 DNA vaccine did not affect cooking loss versus control.
In plain wordsIn goats, a kisspeptin‑54 DNA vaccine did not change cooking loss of meat compared with control goats.
Peptide
Kisspeptin-54 (metastin)
Outcome
No significant changeCooking loss
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Comparator
Control group
Outcome group
Body composition · Metabolic and weight
Source sentences
Summary
Furthermore, PBK-asd immunization did not affect carcass characteristics (dressing percentage, loin area, and fat thickness) and meat quality traits (pH, color, cooking loss, drip loss, and shearing force).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955812
13AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Safety outcome
In buck goats, the PBK-asd kisspeptin‑54 DNA vaccine did not affect drip loss versus control.
In plain wordsIn goats, a kisspeptin‑54 DNA vaccine did not change drip loss of meat compared with control goats.
Peptide
Kisspeptin-54 (metastin)
Outcome
No significant changeDrip loss
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Comparator
Control group
Outcome group
Body composition · Metabolic and weight
Source sentences
Summary
Furthermore, PBK-asd immunization did not affect carcass characteristics (dressing percentage, loin area, and fat thickness) and meat quality traits (pH, color, cooking loss, drip loss, and shearing force).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955813
14AnimalNot a test of Kisspeptin-54 (metastin) aloneAnimal study (in vivo)Safety outcome
In buck goats, the PBK-asd kisspeptin‑54 DNA vaccine did not affect shearing force versus control.
In plain wordsIn goats, a kisspeptin‑54 DNA vaccine did not change meat shearing force compared with control goats.
Peptide
Kisspeptin-54 (metastin)
Outcome
No significant changeShearing force
Study
goat (Yiling bucks)n: not reported in source
Immunocastration DNA vaccine trial in buck goats
Comparator
Control group
Outcome group
Body composition · Metabolic and weight
Source sentences
Summary
Furthermore, PBK-asd immunization did not affect carcass characteristics (dressing percentage, loin area, and fat thickness) and meat quality traits (pH, color, cooking loss, drip loss, and shearing force).
1 context sentence(design, population, supporting numbers)
Summary · context
Thirty buck goats were randomly assigned into three groups: PVAX-B2L-Kisspeptin-54-asd immunized (PBK-asd), control, and surgically castrated.
In this study, Kisspeptin-54 (metastin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-54 (metastin).
Report a problemFND-3228955814

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
13 Oct 2026, 21:44 UTC
Study results updated
Version 1
13 Oct 2026, 16:31 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

Journal Article

MeSH terms

Keywords

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