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Study · Measured the body's own peptide · 2020

7 results

Maternal plasma kisspeptin-10 level in preeclamptic pregnant women and its relation in changing their reproductive hormones.

Al-Kaabi MA, Hamdan FB, Al-Matubsi H

The journal of obstetrics and gynaecology research11 Feb 2020Cited by 6 (Europe PMC)

PMID32045961 (opens in a new tab)DOI10.1111/jog.14208 (opens in a new tab)PepBankPUB-32045961
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

No result from this study comes from a test of the peptide.

Natural levels measured7

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In first-time pregnant women, plasma kisspeptin‑10 levels were lower in women with preeclampsia than in normotensive pregnancies.

    In plain wordsIn pregnant women, the body's own kisspeptin‑10 blood levels were lower in women with preeclampsia than in women with normal blood pressure.

    Peptide
    Kisspeptin-10
    Outcome
    DecreasePlasma kisspeptin-10 in preeclampsia
    Study

    n = 100

    Comparator
    Normotensive pregnancies
    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    Kisspeptin-10 levels were reduced in preeclampsia (PE) women compared with normotensive pregnancies.
    1 context sentence
    Summary · context
    First time pregnant women (n = 100) at 20 weeks of gestation participated in this study and divided into preeclamptics (n = 60) and normotensives (n = 40).

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In the 2nd trimester, plasma kisspeptin‑10 as a marker of preeclampsia had an ROC area of 0.662, sensitivity 55% and specificity 87.5%.

    In plain wordsIn the second trimester, the body's own kisspeptin‑10 level found 55% of preeclampsia cases and correctly ruled out 87.5% of women without it.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableDiagnostic accuracy of plasma KP-10 for preeclampsia, 2nd trimester
    Study

    n = 100

    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Measurements

    ROC AUC
    0.662
    2nd trimester
    Sensitivity
    55%
    2nd trimester
    Specificity
    87.5%
    2nd trimester

    Source sentences

    Summary
    In the 2nd trimester, area under receiver-operator characteristic (ROC) curve was 0.662, positive and negative predictive values were 32.8 and 94.6, and test sensitivity and specificity were 55% and 87.5%, respectively.
    1 context sentence
    Summary · context
    First time pregnant women (n = 100) at 20 weeks of gestation participated in this study and divided into preeclamptics (n = 60) and normotensives (n = 40).

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In the 3rd trimester, plasma kisspeptin‑10 as a marker of preeclampsia had an ROC area of 0.747, sensitivity 83.3% and specificity 67.5%.

    In plain wordsIn the third trimester, the body's own kisspeptin‑10 level found 83.3% of preeclampsia cases and correctly ruled out 67.5% of women without it.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableDiagnostic accuracy of plasma KP-10 for preeclampsia, 3rd trimester
    Study

    n = 100

    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Measurements

    ROC AUC
    0.747
    3rd trimester
    Sensitivity
    83.3%
    3rd trimester
    Specificity
    67.5%
    3rd trimester

    Source sentences

    Summary
    In the 3rd trimester, area under ROC curve was 0.747 positive and negative predictive values were 22.2 and 97.3, and test sensitivity and specificity were 83.3% and 67.5%, respectively.
    1 context sentence
    Summary · context
    First time pregnant women (n = 100) at 20 weeks of gestation participated in this study and divided into preeclamptics (n = 60) and normotensives (n = 40).

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  4. 04HumanEndogenous levelObservational studyOther

    In women with preeclampsia, plasma kisspeptin‑10 correlated inversely with estradiol in the 2nd trimester.

    In plain wordsIn women with preeclampsia, the body's own kisspeptin‑10 level was linked to lower estradiol in the second trimester.

    Peptide
    Kisspeptin-10
    Outcome
    DecreaseCorrelation of KP-10 with estradiol, 2nd trimester
    Study

    n = 60

    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    In PE patients, plasma KP-10 demonstrated an inverse correlation with E2 (during the 2nd trimester), LH and FSH (during the 3rd trimester), and positively correlated with β-hCG (during the 3rd trimester).
    1 context sentence
    Summary · context
    First time pregnant women (n = 100) at 20 weeks of gestation participated in this study and divided into preeclamptics (n = 60) and normotensives (n = 40).

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  5. 05HumanEndogenous levelObservational studyOther

    In women with preeclampsia, plasma kisspeptin‑10 correlated inversely with luteinizing hormone in the 3rd trimester.

    In plain wordsIn women with preeclampsia, the body's own kisspeptin‑10 level was linked to lower luteinizing hormone in the third trimester.

    Peptide
    Kisspeptin-10
    Outcome
    DecreaseCorrelation of KP-10 with LH, 3rd trimester
    Study

    n = 60

    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    In PE patients, plasma KP-10 demonstrated an inverse correlation with E2 (during the 2nd trimester), LH and FSH (during the 3rd trimester), and positively correlated with β-hCG (during the 3rd trimester).
    1 context sentence
    Summary · context
    First time pregnant women (n = 100) at 20 weeks of gestation participated in this study and divided into preeclamptics (n = 60) and normotensives (n = 40).

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  6. 06HumanEndogenous levelObservational studyOther

    In women with preeclampsia, plasma kisspeptin‑10 correlated inversely with follicle stimulating hormone in the 3rd trimester.

    In plain wordsIn women with preeclampsia, the body's own kisspeptin‑10 level was linked to lower follicle stimulating hormone in the third trimester.

    Peptide
    Kisspeptin-10
    Outcome
    DecreaseCorrelation of KP-10 with FSH, 3rd trimester
    Study

    n = 60

    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    In PE patients, plasma KP-10 demonstrated an inverse correlation with E2 (during the 2nd trimester), LH and FSH (during the 3rd trimester), and positively correlated with β-hCG (during the 3rd trimester).
    1 context sentence
    Summary · context
    First time pregnant women (n = 100) at 20 weeks of gestation participated in this study and divided into preeclamptics (n = 60) and normotensives (n = 40).

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  7. 07HumanEndogenous levelObservational studyOther

    In women with preeclampsia, plasma kisspeptin‑10 correlated positively with beta-hCG in the 3rd trimester.

    In plain wordsIn women with preeclampsia, the body's own kisspeptin‑10 level was linked to higher beta-hCG in the third trimester.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseCorrelation of KP-10 with beta-hCG, 3rd trimester
    Study

    n = 60

    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    In PE patients, plasma KP-10 demonstrated an inverse correlation with E2 (during the 2nd trimester), LH and FSH (during the 3rd trimester), and positively correlated with β-hCG (during the 3rd trimester).
    2 context sentences
    Summary · context
    Furthermore, KP-10 in PE patients demonstrated significant positive correlation with β-hCG.
    Summary · context
    First time pregnant women (n = 100) at 20 weeks of gestation participated in this study and divided into preeclamptics (n = 60) and normotensives (n = 40).

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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