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Study · Non-randomized trial · n = 8 · 2019

2 results

CHANGES IN IRISIN RELEASE IN RESPONSE TO PERIPHERAL KISSPEPTIN-10 ADMINISTRATION IN HEALTHY AND OBESE ADULT MEN.

Shamas S, Rani S, Afsheen S, Shahab M, Ejaz R, Sadia H, Khan L, Rehman TU, Roshan S, Mayo A

Acta endocrinologica (Bucharest, Romania : 2005)1 Jul 2019Cited by 3 (Europe PMC)

PMID32010344 (opens in a new tab)PMCIDPMC6992392 (opens in a new tab)DOI10.4183/aeb.2019.283 (opens in a new tab)PepBankPUB-32010344
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In normal weight men, plasma irisin was significantly higher at 210 minutes after kisspeptin‑10 than before it.

    In plain wordsIn normal weight men, blood irisin was higher 210 minutes after kisspeptin‑10 than before it.

    Peptide
    Kisspeptin-10
    Outcome
    IncreasePlasma irisin at 210 min after kisspeptin-10, normal weight men
    Study

    n = 8

    Healthy normal weight men
    Outcome group
    Hormone levels · Metabolic and weight
    Studied dose
    Dose not stated · peripheral injectionAs given in this study (human).

    Measurements

    Plasma irisin
    96.24 ng/mL
    normal weight, 210 min post-kisspeptin
    Plasma irisin
    59.18 ng/mL
    normal weight, pre-kisspeptin

    Source sentences

    Summary
    Mean irisin levels (96.24 ± 1.351 ng/mL) at 210 minutes were significantly (P<0.0001) enhanced as compared to pre-kisspeptin (59.18 ± 4.815 ng/mL) in normal weight subjects.
    1 context sentence
    Summary · context
    Kisspeptin-10 was administered to normal weight (n=8) and obese (n=8) men.
  2. 02HumanNon-randomized trialEfficacy outcome

    In obese men, plasma irisin was significantly higher at 180 minutes after kisspeptin‑10 than before it.

    In plain wordsIn obese men, blood irisin was higher 180 minutes after kisspeptin‑10 than before it.

    Peptide
    Kisspeptin-10
    Outcome
    IncreasePlasma irisin at 180 min after kisspeptin-10, obese men
    Study

    n = 8

    Obese men
    Outcome group
    Hormone levels · Metabolic and weight
    Studied dose
    Dose not stated · peripheral injectionAs given in this study (human).

    Measurements

    Plasma irisin
    75.76 ng/mL
    obese, 180 min post-kisspeptin
    Plasma irisin
    41.28 ng/mL
    obese, pre-kisspeptin

    Source sentences

    Summary
    In obese subjects mean irisin levels (75.76 ± 4.06 ng/mL) were significantly (P<0.0001) elevated at 180 minutes post-kisspeptin when compared with pre-kisspeptin irisin levels (41.28 ± 2.89 ng/mL).
    1 context sentence
    Summary · context
    Kisspeptin-10 was administered to normal weight (n=8) and obese (n=8) men.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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