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Study · Systematic review · n = 492 · 2020

4 results

Analysis of the effect of liraglutide on glycemic variability in patients with type 2 diabetes.

Xing Y, Chen J, Zhao L, Ma H

Endocrine journal28 Jan 2020Cited by 6 (Europe PMC)

PMID31996492 (opens in a new tab)DOI10.1507/endocrj.ej19-0530 (opens in a new tab)PepBankPUB-31996492
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanSystematic reviewEfficacy outcome

    In adults with type 2 diabetes, a meta-analysis found lower MAGE after liraglutide treatment than before treatment.

    In plain wordsIn adults with type 2 diabetes, blood sugar swings (MAGE) were smaller after liraglutide than before it.

    Peptide
    Liraglutide
    Outcome
    DecreaseMAGE (mean amplitude of glycemic excursion)
    Study

    n = 492

    Comparator
    Before liraglutide treatment
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Compared with the patients before the treatment, the patients after the treatment had a smaller glycemic variability (MAGE: I2 = 92%, p < 0.01, Z = 11.91, p < 0.01, MD = -2.78, 95%CI: -3.24 - -2.32
    2 context sentences
    Summary · context
    A total of 16 studies were included in the meta-analysis involving 492 participants.
    Summary · context
    The glycemic variability indexes of patients before and after treatment with liraglutide were compared.
  2. 02HumanSystematic reviewEfficacy outcome

    In adults with type 2 diabetes, a meta-analysis found lower LAGE after liraglutide treatment than before treatment.

    In plain wordsIn adults with type 2 diabetes, the largest blood sugar swings (LAGE) were smaller after liraglutide than before it.

    Peptide
    Liraglutide
    Outcome
    DecreaseLAGE (largest amplitude of glycemic excursions)
    Study

    n = 492

    Comparator
    Before liraglutide treatment
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Compared with the patients before the treatment, the patients after the treatment had a smaller glycemic variability
    3 context sentences
    Summary · context
    LAGE: I2 = 76%, p = 0.08, Z = 9.94, p < 0.01, MD = -2.20, 95%CI: -2.59 - -1.81
    Summary · context
    A total of 16 studies were included in the meta-analysis involving 492 participants.
    Summary · context
    The glycemic variability indexes of patients before and after treatment with liraglutide were compared.
  3. 03HumanSystematic reviewEfficacy outcome

    In adults with type 2 diabetes, a meta-analysis found lower MODD after liraglutide treatment than before treatment.

    In plain wordsIn adults with type 2 diabetes, day-to-day blood sugar differences (MODD) were smaller after liraglutide than before it.

    Peptide
    Liraglutide
    Outcome
    DecreaseMODD (mean of daily differences)
    Study

    n = 492

    Comparator
    Before liraglutide treatment
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Compared with the patients before the treatment, the patients after the treatment had a smaller glycemic variability
    3 context sentences
    Summary · context
    MODD: I2 = 74%, p = 0.002, Z = 14.03, p < 0.01, MD = -0.90, 95%CI: -1.02 - -0.77
    Summary · context
    A total of 16 studies were included in the meta-analysis involving 492 participants.
    Summary · context
    The glycemic variability indexes of patients before and after treatment with liraglutide were compared.
  4. 04HumanSystematic reviewEfficacy outcome

    In adults with type 2 diabetes, a meta-analysis found a lower standard deviation of blood glucose after liraglutide treatment than before treatment.

    In plain wordsIn adults with type 2 diabetes, blood sugar variation (standard deviation) was smaller after liraglutide than before it.

    Peptide
    Liraglutide
    Outcome
    DecreaseSD of blood glucose
    Study

    n = 492

    Comparator
    Before liraglutide treatment
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Compared with the patients before the treatment, the patients after the treatment had a smaller glycemic variability
    3 context sentences
    Summary · context
    SD: I2 = 93%, p < 0.01, Z = 3.62, p < 0.01, SMD = -1.77, 95%CI: -2.73 - -0.81
    Summary · context
    A total of 16 studies were included in the meta-analysis involving 492 participants.
    Summary · context
    The glycemic variability indexes of patients before and after treatment with liraglutide were compared.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 11:11 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:05 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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