In patients with advanced enteropancreatic NETs, lanreotide's therapeutic effect versus placebo did not depend on NLR.
In plain wordsIn patients with advanced NETs, lanreotide's effect versus placebo did not depend on NLR.
- Peptide
- Lanreotide
- Outcome
- No significant changeTreatment effect by NLR
- Study
n: not reported in source
- Comparator
- Placebo
- Analysis
- Exploratory
- Outcome group
- Tumor growth · Cancer
- Studied dose
- 120 mgAs given in this study (human).
Measurements
- P value for treatment effect by NLR
- > 0.1
- lanreotide versus placebo, across NLR subgroups
Source sentences
The therapeutic effect of lanreotide autogel/depot 120 mg was independent of NLRs (P > 0.1).
1 context sentence(design, population, supporting numbers)
In the randomized double-blind CLARINET study (NCT00353496; EudraCT 2005-004904-35), the somatostatin analog lanreotide autogel/depot increased progression-free survival (PFS) compared with placebo in patients with inoperable or metastatic intestinal and pancreatic NETs (grades 1-2, Ki-67 < 10%).