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Study · Animal study (in vivo) · horse · 2020

4 results

Single injection of triptorelin or buserelin acetate in saline solution induces ovulation in mares the same as a single injection of hCG.

Dordas-Perpinyà M, Normandin L, Dhier T, Terris H, Cochard A, Frilley C, Huiban F, Bruyas JF

Reproduction in domestic animals = Zuchthygiene31 Jan 2020Cited by 6 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mares, triptorelin and hCG showed similar ovulation efficacy within 24-48 hours.

    In plain wordsIn mares, triptorelin produced similar ovulation efficacy to hCG.

    Outcome
    No significant changeOvulation within 24-48 hours
    Study

    horsen: not reported in source

    mares with growing pre-ovulatory follicles
    Comparator
    hCG 1,500 IU
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.1 mg · subcutaneous · single injectionAs given in this study (horse).

    Measurements

    Ovulation
    84.7%
    triptorelin 0.1 mg

    Source sentences

    Summary
    experiment 3: hCG (87% n = 106), buserelin 3 mg (84,7% n = 137), buserelin 2 mg (82,7% n = 104), buserelin 1 mg (87% n = 54) and triptorelin 0.1 mg (84,7% n = 72).
    2 context sentences
    Summary · context
    This study also shows that a injection of 0.1 mg of triptorelin in solution is a good alternative for ovulation induction and is comparable to small doses of buserelin acetate in solution (1 mg) and 1,500 IU of the gold standard trigger hCG, mainly in countries where human formulation of buserelin is not available.
    Summary · context
    The aim of this study was to assess the efficacy of different doses of buserelin acetate and another GnRH agonist, triptorelin acetate, in saline solution in a single subcutaneous injection, to induce ovulation of growing pre-ovulatory follicle in mare and compare it with the classical treatment of…
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In mares, triptorelin and buserelin 3 mg showed similar ovulation efficacy.

    In plain wordsIn mares, triptorelin produced similar ovulation efficacy to buserelin 3 mg.

    Outcome
    No significant changeOvulation within 24-48 hours
    Study

    horsen: not reported in source

    mares with growing pre-ovulatory follicles
    Comparator
    buserelin 3 mg
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.1 mg · subcutaneous · single injectionAs given in this study (horse).

    Source sentences

    Summary
    The results of all experiments showed the same efficacy between all treatments with mares ovulating between 24 and 48 hr after injection:
    2 context sentences
    Summary · context
    experiment 3: hCG (87% n = 106), buserelin 3 mg (84,7% n = 137), buserelin 2 mg (82,7% n = 104), buserelin 1 mg (87% n = 54) and triptorelin 0.1 mg (84,7% n = 72).
    Summary · context
    The aim of this study was to assess the efficacy of different doses of buserelin acetate and another GnRH agonist, triptorelin acetate, in saline solution in a single subcutaneous injection, to induce ovulation of growing pre-ovulatory follicle in mare and compare it with the classical treatment of…
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In mares, triptorelin and buserelin 2 mg showed similar ovulation efficacy.

    In plain wordsIn mares, triptorelin produced similar ovulation efficacy to buserelin 2 mg.

    Outcome
    No significant changeOvulation within 24-48 hours
    Study

    horsen: not reported in source

    mares with growing pre-ovulatory follicles
    Comparator
    buserelin 2 mg
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.1 mg · subcutaneous · single injectionAs given in this study (horse).

    Source sentences

    Summary
    The results of all experiments showed the same efficacy between all treatments with mares ovulating between 24 and 48 hr after injection:
    2 context sentences
    Summary · context
    experiment 3: hCG (87% n = 106), buserelin 3 mg (84,7% n = 137), buserelin 2 mg (82,7% n = 104), buserelin 1 mg (87% n = 54) and triptorelin 0.1 mg (84,7% n = 72).
    Summary · context
    The aim of this study was to assess the efficacy of different doses of buserelin acetate and another GnRH agonist, triptorelin acetate, in saline solution in a single subcutaneous injection, to induce ovulation of growing pre-ovulatory follicle in mare and compare it with the classical treatment of…
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In mares, triptorelin and buserelin 1 mg showed similar ovulation efficacy.

    In plain wordsIn mares, triptorelin produced similar ovulation efficacy to buserelin 1 mg.

    Outcome
    No significant changeOvulation within 24-48 hours
    Study

    horsen: not reported in source

    mares with growing pre-ovulatory follicles
    Comparator
    buserelin 1 mg
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.1 mg · subcutaneous · single injectionAs given in this study (horse).

    Source sentences

    Summary
    The results of all experiments showed the same efficacy between all treatments with mares ovulating between 24 and 48 hr after injection:
    2 context sentences
    Summary · context
    experiment 3: hCG (87% n = 106), buserelin 3 mg (84,7% n = 137), buserelin 2 mg (82,7% n = 104), buserelin 1 mg (87% n = 54) and triptorelin 0.1 mg (84,7% n = 72).
    Summary · context
    The aim of this study was to assess the efficacy of different doses of buserelin acetate and another GnRH agonist, triptorelin acetate, in saline solution in a single subcutaneous injection, to induce ovulation of growing pre-ovulatory follicle in mare and compare it with the classical treatment of…

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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