Kisspeptin injection improved the semen characteristics and sperm rheotaxis in Ossimi ram.

El-Sherry TM, Abdel-Ghani MA, Mahmoud GB, Ezzat AA

Reproduction in domestic animals = Zuchthygiene23 Jan 2020Cited by 8 (Europe PMC)

PMID31880370DOI10.1111/rda.13613PepBankPUB-31880370

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. No result from this study comes from people.

01AnimalAnimal study (in vivo)Efficacy outcome
In immature Ossimi rams, kisspeptin‑10 injection increased semen volume compared with saline control.
In plain wordsIn young rams, kisspeptin‑10 injections increased semen volume compared with saline.
Peptide
Kisspeptin-10
Outcome
IncreaseSemen volume
Study
sheepn: not reported in source
Immature Ossimi rams
Comparator
Saline
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 µg/kg body weight · intramuscular · once a week for 1 monthAs given in this study (sheep).
Source sentences
Summary
The Kp10 increased the volume, sperm concentration and percentages of live sperm compared with those of control.
2 context sentences(design, population, supporting numbers)
Summary · context
Healthy Ossimi rams were randomly divided into two groups; a saline-treated control group and Kp10-treated one (5 µg/kg body weight).
Summary · context
Treatments were given by intramuscular injection once a week for 1 month.
Report a problemFND-3188037001
02AnimalAnimal study (in vivo)Efficacy outcome
In immature Ossimi rams, kisspeptin‑10 injection increased sperm concentration compared with saline control.
In plain wordsIn young rams, kisspeptin‑10 injections increased sperm concentration compared with saline.
Peptide
Kisspeptin-10
Outcome
IncreaseSperm concentration
Study
sheepn: not reported in source
Immature Ossimi rams
Comparator
Saline
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 µg/kg body weight · intramuscular · once a week for 1 monthAs given in this study (sheep).
Source sentences
Summary
The Kp10 increased the volume, sperm concentration and percentages of live sperm compared with those of control.
2 context sentences(design, population, supporting numbers)
Summary · context
Healthy Ossimi rams were randomly divided into two groups; a saline-treated control group and Kp10-treated one (5 µg/kg body weight).
Summary · context
Treatments were given by intramuscular injection once a week for 1 month.
Report a problemFND-3188037002
03AnimalAnimal study (in vivo)Efficacy outcome
In immature Ossimi rams, kisspeptin‑10 injection increased the percentage of live sperm compared with saline control.
In plain wordsIn young rams, kisspeptin‑10 injections increased the share of live sperm compared with saline.
Peptide
Kisspeptin-10
Outcome
IncreasePercentage of live sperm
Study
sheepn: not reported in source
Immature Ossimi rams
Comparator
Saline
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 µg/kg body weight · intramuscular · once a week for 1 monthAs given in this study (sheep).
Source sentences
Summary
The Kp10 increased the volume, sperm concentration and percentages of live sperm compared with those of control.
2 context sentences(design, population, supporting numbers)
Summary · context
Healthy Ossimi rams were randomly divided into two groups; a saline-treated control group and Kp10-treated one (5 µg/kg body weight).
Summary · context
Treatments were given by intramuscular injection once a week for 1 month.
Report a problemFND-3188037003
04AnimalAnimal study (in vivo)Efficacy outcome
In immature Ossimi rams, sperm trajectories improved with kisspeptin‑10 injection over time.
In plain wordsIn young rams, sperm movement paths improved over time with kisspeptin‑10 injections.
Peptide
Kisspeptin-10
Outcome
Direction not reportedSperm trajectories
Study
sheepn: not reported in source
Immature Ossimi rams
Comparator
Saline
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 µg/kg body weight · intramuscular · once a week for 1 monthAs given in this study (sheep).
Source sentences
Summary
Additionally, sperm trajectories and rheotaxis get improved by the injection of Kp10 with time.
2 context sentences(design, population, supporting numbers)
Summary · context
Healthy Ossimi rams were randomly divided into two groups; a saline-treated control group and Kp10-treated one (5 µg/kg body weight).
Summary · context
Treatments were given by intramuscular injection once a week for 1 month.
Report a problemFND-3188037004
05AnimalAnimal study (in vivo)Efficacy outcome
In immature Ossimi rams, sperm rheotaxis improved with kisspeptin‑10 injection over time.
In plain wordsIn young rams, the ability of sperm to swim against flow improved over time with kisspeptin‑10 injections.
Peptide
Kisspeptin-10
Outcome
IncreaseSperm positive rheotaxis
Study
sheepn: not reported in source
Immature Ossimi rams
Comparator
Saline
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 µg/kg body weight · intramuscular · once a week for 1 monthAs given in this study (sheep).
Source sentences
Summary
Additionally, sperm trajectories and rheotaxis get improved by the injection of Kp10 with time.
3 context sentences(design, population, supporting numbers)
Summary · context
PR % was defined as the number of PR sperms over the number of motile sperms.
Summary · context
Healthy Ossimi rams were randomly divided into two groups; a saline-treated control group and Kp10-treated one (5 µg/kg body weight).
Summary · context
Treatments were given by intramuscular injection once a week for 1 month.
Report a problemFND-3188037005
06AnimalAnimal study (in vivo)Efficacy outcome
In immature Ossimi rams, kisspeptin‑10 improved testosterone secretion throughout the study period.
In plain wordsIn young rams, kisspeptin‑10 injections increased testosterone levels throughout the study.
Peptide
Kisspeptin-10
Outcome
IncreaseTestosterone secretion
Study
sheepn: not reported in source
Immature Ossimi rams
Comparator
Saline
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
5 µg/kg body weight · intramuscular · once a week for 1 monthAs given in this study (sheep).
Source sentences
Summary
Furthermore, kisspeptin improved the secretion of testosterone levels throughout the period of study.
2 context sentences(design, population, supporting numbers)
Summary · context
Healthy Ossimi rams were randomly divided into two groups; a saline-treated control group and Kp10-treated one (5 µg/kg body weight).
Summary · context
Treatments were given by intramuscular injection once a week for 1 month.
Report a problemFND-3188037006

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
10 Oct 2026, 09:43 UTC
Study results updated
Version 1
9 Oct 2026, 03:04 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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