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Study · Ex vivo tissue · 2020

3 results

Carnosine treatment during human semen processing by discontinuous density gradient.

Adami LNG, de Lima BT, Andretta RR, Bertolla RP, Nichi M

Andrologia3 Dec 2019Cited by 3 (Europe PMC)

PMID31793048 (opens in a new tab)DOI10.1111/and.13497 (opens in a new tab)PepBankPUB-31793048
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueEfficacy outcome

    In human semen samples, carnosine improved sperm mitochondrial activity compared with untreated samples.

    In plain wordsIn lab tests, carnosine improved sperm mitochondrial activity compared with untreated samples.

    Peptide
    L-carnosine
    Outcome
    IncreaseSperm mitochondrial activity
    Study

    humann: not reported in source

    Human semen samples
    Comparator
    Untreated samples
    Outcome group
    Mitochondrial function · Reproductive and sexual health
    Studied dose
    50 mMAs given in this study (human).

    Source sentences

    Summary
    The 50 mM carnosine supplementation led to improved sperm mitochondrial activity when compared to untreated samples.
    1 context sentence
    Summary · context
    Semen samples from 34 patients were submitted to processing by discontinuous density gradient centrifugation without (control)
  2. 02LabEx vivo tissueActivity measurement

    In human semen samples, motility measures improved after processing irrespective of carnosine supplementation.

    In plain wordsIn lab tests, sperm motility measures improved after processing with or without carnosine.

    Peptide
    L-carnosine
    Outcome
    Not applicableMotility after processing
    Study

    humann: not reported in source

    Human semen samples
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Motility variables, such as percentage of motile and progressively motile spermatozoa, average path velocity, straight line velocity, curvilinear velocity and linearity, showed an improvement after semen processing irrespective of carnosine supplementation.
    1 context sentence
    Summary · context
    Semen samples from 34 patients were submitted to processing by discontinuous density gradient centrifugation without (control)
  3. 03LabEx vivo tissueEfficacy outcome

    In human semen samples, both carnosine concentrations increased beat-cross frequency compared with samples before processing.

    In plain wordsIn lab tests, both carnosine concentrations increased sperm beat-cross frequency compared with samples before processing.

    Peptide
    L-carnosine
    Outcome
    IncreaseBeat-cross frequency
    Study

    humann: not reported in source

    Human semen samples
    Comparator
    Samples before processing
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    20 and 50 mMAs given in this study (human).

    Source sentences

    Summary
    Both concentrations of carnosine increased the beat-cross frequency (BCF) when compared to samples before processing.
    2 context sentences
    Summary · context
    (a) 20 mM of carnosine supplementation on the layers of Percoll; and (b) 50 mM carnosine supplementation.
    Summary · context
    Semen samples from 34 patients were submitted to processing by discontinuous density gradient centrifugation without (control)

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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