Reproductive, antioxidant and metabolic responses of Ossimi rams to kisspeptin.

Abou Khalil NS, Mahmoud GB

Theriogenology1 Nov 2019Cited by 10 (Europe PMC)

PMID31711707DOI10.1016/j.theriogenology.2019.10.039PepBankPUB-31711707

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study12

12 results from studies that gave the peptide. No result from this study comes from people.

01AnimalAnimal study (in vivo)Efficacy outcome
In Ossimi rams, KP-10 significantly improved all semen characteristics compared with the control group and with pre-treatment values.
In plain wordsIn rams, kisspeptin‑10 improved all measured semen characteristics compared with untreated rams and with before treatment.
Peptide
Kisspeptin-10
Outcome
IncreaseSemen characteristics
Study
sheepn = 12
Ossimi rams
Comparator
Control group (and pre-treatment values)
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 μg/kg body weight, once weekly · one monthAs given in this study (sheep).
Source sentences
Summary
However, all semen characteristics were significantly improved in the treated group compared with the control group at the post-treatment period and in the treated group at the post-treatment period compared with that at the pre-treatment period.
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve Ossimi rams (1.5-2 years old) were divided randomly into two groups (six per group).
Summary · context
Rams of the treated group were injected once weekly with KP-10 (5 μg/kg body weight) for one month.
Report a problemFND-3171170701
02AnimalAnimal study (in vivo)Efficacy outcome
In Ossimi rams, KP-10 improved scrotal circumference compared with the control group and with pre-treatment values.
In plain wordsIn rams, kisspeptin‑10 increased scrotal circumference compared with untreated rams and with before treatment.
Peptide
Kisspeptin-10
Outcome
IncreaseScrotal circumference
Study
sheepn = 12
Ossimi rams
Comparator
Control group (and pre-treatment values)
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 μg/kg body weight, once weekly · one monthAs given in this study (sheep).
Source sentences
Summary
scrotal circumference, ejaculate volume and total sperm concentration/ejaculate showed higher significant improvements
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve Ossimi rams (1.5-2 years old) were divided randomly into two groups (six per group).
Summary · context
Rams of the treated group were injected once weekly with KP-10 (5 μg/kg body weight) for one month.
Report a problemFND-3171170702
03AnimalAnimal study (in vivo)Efficacy outcome
In Ossimi rams, KP-10 improved ejaculate volume compared with the control group and with pre-treatment values.
In plain wordsIn rams, kisspeptin‑10 increased ejaculate volume compared with untreated rams and with before treatment.
Peptide
Kisspeptin-10
Outcome
IncreaseEjaculate volume
Study
sheepn = 12
Ossimi rams
Comparator
Control group (and pre-treatment values)
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 μg/kg body weight, once weekly · one monthAs given in this study (sheep).
Source sentences
Summary
scrotal circumference, ejaculate volume and total sperm concentration/ejaculate showed higher significant improvements
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve Ossimi rams (1.5-2 years old) were divided randomly into two groups (six per group).
Summary · context
Rams of the treated group were injected once weekly with KP-10 (5 μg/kg body weight) for one month.
Report a problemFND-3171170703
04AnimalAnimal study (in vivo)Efficacy outcome
In Ossimi rams, KP-10 improved total sperm concentration per ejaculate compared with the control group and with pre-treatment values.
In plain wordsIn rams, kisspeptin‑10 increased the total sperm count per ejaculate compared with untreated rams and with before treatment.
Peptide
Kisspeptin-10
Outcome
IncreaseTotal sperm concentration per ejaculate
Study
sheepn = 12
Ossimi rams
Comparator
Control group (and pre-treatment values)
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 μg/kg body weight, once weekly · one monthAs given in this study (sheep).
Source sentences
Summary
scrotal circumference, ejaculate volume and total sperm concentration/ejaculate showed higher significant improvements
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve Ossimi rams (1.5-2 years old) were divided randomly into two groups (six per group).
Summary · context
Rams of the treated group were injected once weekly with KP-10 (5 μg/kg body weight) for one month.
Report a problemFND-3171170704
05AnimalAnimal study (in vivo)Efficacy outcome
In Ossimi rams, KP-10 increased serum testosterone compared with the control group and with pre-treatment values.
In plain wordsIn rams, kisspeptin‑10 raised testosterone compared with untreated rams and with before treatment.
Peptide
Kisspeptin-10
Outcome
IncreaseSerum testosterone
Study
sheepn = 12
Ossimi rams
Comparator
Control group (and pre-treatment values)
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
5 μg/kg body weight, once weekly · one monthAs given in this study (sheep).
Source sentences
Summary
Serum testosterone, total antioxidant capacity, lipid peroxides, nitric oxide, total protein, albumin, glucose and high density lipoprotein-cholesterol levels significantly increased when comparing the treated group with the control one at the post-treatment period and also when comparing the treate…
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve Ossimi rams (1.5-2 years old) were divided randomly into two groups (six per group).
Summary · context
Rams of the treated group were injected once weekly with KP-10 (5 μg/kg body weight) for one month.
Report a problemFND-3171170705
06AnimalAnimal study (in vivo)Efficacy outcome
In Ossimi rams, KP-10 increased total antioxidant capacity compared with the control group and with pre-treatment values.
In plain wordsIn rams, kisspeptin‑10 raised total antioxidant capacity compared with untreated rams and with before treatment.
Peptide
Kisspeptin-10
Outcome
IncreaseTotal antioxidant capacity
Study
sheepn = 12
Ossimi rams
Comparator
Control group (and pre-treatment values)
Outcome group
Oxidative stress · Whole body
Studied dose
5 μg/kg body weight, once weekly · one monthAs given in this study (sheep).
Source sentences
Summary
Serum testosterone, total antioxidant capacity, lipid peroxides, nitric oxide, total protein, albumin, glucose and high density lipoprotein-cholesterol levels significantly increased when comparing the treated group with the control one at the post-treatment period and also when comparing the treate…
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve Ossimi rams (1.5-2 years old) were divided randomly into two groups (six per group).
Summary · context
Rams of the treated group were injected once weekly with KP-10 (5 μg/kg body weight) for one month.
Report a problemFND-3171170706
07AnimalAnimal study (in vivo)Efficacy outcome
In Ossimi rams, KP-10 increased lipid peroxides compared with the control group and with pre-treatment values.
In plain wordsIn rams, kisspeptin‑10 raised lipid peroxide levels compared with untreated rams and with before treatment.
Peptide
Kisspeptin-10
Outcome
IncreaseLipid peroxides
Study
sheepn = 12
Ossimi rams
Comparator
Control group (and pre-treatment values)
Outcome group
Oxidative stress · Whole body
Studied dose
5 μg/kg body weight, once weekly · one monthAs given in this study (sheep).
Source sentences
Summary
Serum testosterone, total antioxidant capacity, lipid peroxides, nitric oxide, total protein, albumin, glucose and high density lipoprotein-cholesterol levels significantly increased when comparing the treated group with the control one at the post-treatment period and also when comparing the treate…
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve Ossimi rams (1.5-2 years old) were divided randomly into two groups (six per group).
Summary · context
Rams of the treated group were injected once weekly with KP-10 (5 μg/kg body weight) for one month.
Report a problemFND-3171170707
08AnimalAnimal study (in vivo)Efficacy outcome
In Ossimi rams, KP-10 increased nitric oxide compared with the control group and with pre-treatment values.
In plain wordsIn rams, kisspeptin‑10 raised nitric oxide levels compared with untreated rams and with before treatment.
Peptide
Kisspeptin-10
Outcome
IncreaseNitric oxide
Study
sheepn = 12
Ossimi rams
Comparator
Control group (and pre-treatment values)
Outcome group
Oxidative stress · Whole body
Studied dose
5 μg/kg body weight, once weekly · one monthAs given in this study (sheep).
Source sentences
Summary
Serum testosterone, total antioxidant capacity, lipid peroxides, nitric oxide, total protein, albumin, glucose and high density lipoprotein-cholesterol levels significantly increased when comparing the treated group with the control one at the post-treatment period and also when comparing the treate…
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve Ossimi rams (1.5-2 years old) were divided randomly into two groups (six per group).
Summary · context
Rams of the treated group were injected once weekly with KP-10 (5 μg/kg body weight) for one month.
Report a problemFND-3171170708
09AnimalAnimal study (in vivo)Efficacy outcome
In Ossimi rams, KP-10 increased total protein compared with the control group and with pre-treatment values.
In plain wordsIn rams, kisspeptin‑10 raised blood total protein compared with untreated rams and with before treatment.
Peptide
Kisspeptin-10
Outcome
IncreaseTotal protein
Study
sheepn = 12
Ossimi rams
Comparator
Control group (and pre-treatment values)
Outcome group
Metabolic pathways and metabolomics · Metabolic and weight
Studied dose
5 μg/kg body weight, once weekly · one monthAs given in this study (sheep).
Source sentences
Summary
Serum testosterone, total antioxidant capacity, lipid peroxides, nitric oxide, total protein, albumin, glucose and high density lipoprotein-cholesterol levels significantly increased when comparing the treated group with the control one at the post-treatment period and also when comparing the treate…
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve Ossimi rams (1.5-2 years old) were divided randomly into two groups (six per group).
Summary · context
Rams of the treated group were injected once weekly with KP-10 (5 μg/kg body weight) for one month.
Report a problemFND-3171170709
10AnimalAnimal study (in vivo)Efficacy outcome
In Ossimi rams, KP-10 increased albumin compared with the control group and with pre-treatment values.
In plain wordsIn rams, kisspeptin‑10 raised blood albumin compared with untreated rams and with before treatment.
Peptide
Kisspeptin-10
Outcome
IncreaseAlbumin
Study
sheepn = 12
Ossimi rams
Comparator
Control group (and pre-treatment values)
Outcome group
Metabolic pathways and metabolomics · Metabolic and weight
Studied dose
5 μg/kg body weight, once weekly · one monthAs given in this study (sheep).
Source sentences
Summary
Serum testosterone, total antioxidant capacity, lipid peroxides, nitric oxide, total protein, albumin, glucose and high density lipoprotein-cholesterol levels significantly increased when comparing the treated group with the control one at the post-treatment period and also when comparing the treate…
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve Ossimi rams (1.5-2 years old) were divided randomly into two groups (six per group).
Summary · context
Rams of the treated group were injected once weekly with KP-10 (5 μg/kg body weight) for one month.
Report a problemFND-3171170710
11AnimalAnimal study (in vivo)Efficacy outcome
In Ossimi rams, KP-10 increased glucose compared with the control group and with pre-treatment values.
In plain wordsIn rams, kisspeptin‑10 raised blood glucose compared with untreated rams and with before treatment.
Peptide
Kisspeptin-10
Outcome
IncreaseGlucose
Study
sheepn = 12
Ossimi rams
Comparator
Control group (and pre-treatment values)
Outcome group
Glycemic control · Metabolic and weight
Studied dose
5 μg/kg body weight, once weekly · one monthAs given in this study (sheep).
Source sentences
Summary
Serum testosterone, total antioxidant capacity, lipid peroxides, nitric oxide, total protein, albumin, glucose and high density lipoprotein-cholesterol levels significantly increased when comparing the treated group with the control one at the post-treatment period and also when comparing the treate…
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve Ossimi rams (1.5-2 years old) were divided randomly into two groups (six per group).
Summary · context
Rams of the treated group were injected once weekly with KP-10 (5 μg/kg body weight) for one month.
Report a problemFND-3171170711
12AnimalAnimal study (in vivo)Efficacy outcome
In Ossimi rams, KP-10 increased high density lipoprotein-cholesterol compared with the control group and with pre-treatment values.
In plain wordsIn rams, kisspeptin‑10 raised HDL cholesterol compared with untreated rams and with before treatment.
Peptide
Kisspeptin-10
Outcome
IncreaseHDL-cholesterol
Study
sheepn = 12
Ossimi rams
Comparator
Control group (and pre-treatment values)
Outcome group
Lipids · Metabolic and weight
Studied dose
5 μg/kg body weight, once weekly · one monthAs given in this study (sheep).
Source sentences
Summary
Serum testosterone, total antioxidant capacity, lipid peroxides, nitric oxide, total protein, albumin, glucose and high density lipoprotein-cholesterol levels significantly increased when comparing the treated group with the control one at the post-treatment period and also when comparing the treate…
2 context sentences(design, population, supporting numbers)
Summary · context
Twelve Ossimi rams (1.5-2 years old) were divided randomly into two groups (six per group).
Summary · context
Rams of the treated group were injected once weekly with KP-10 (5 μg/kg body weight) for one month.
Report a problemFND-3171170712

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
9 Oct 2026, 18:17 UTC
Study results updated
Version 1
9 Oct 2026, 03:04 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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Reproductive, antioxidant and metabolic responses of Ossimi rams to kisspeptin.

Summary

Results from this study12

Version history

Subjects

Publication types

MeSH terms

Keywords