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Study · Measured the body's own peptide · 2019

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Effects of prolonged type 2 diabetes on mitochondrial function in cerebral blood vessels.

Merdzo I, Rutkai I, Sure VNLR, Katakam PVG, Busija DW

American journal of physiology. Heart and circulatory physiology6 Sept 2019Cited by 10 (Europe PMC)

PMID31490734 (opens in a new tab)PMCIDPMC6879912 (opens in a new tab)DOI10.1152/ajpheart.00341.2019 (opens in a new tab)PepBankPUB-31490734
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In Zucker diabetic fatty rats, levels of rattin, a rat humanin analog, tended to decrease versus lean controls but not significantly (P = 0.08).

    In plain wordsIn diabetic rats, the body's own rattin, a rat humanin analog, tended to be lower than in lean rats, but not significantly.

    Peptide
    Humanin
    Outcome
    No significant changeRattin level in cerebral vessels
    Study

    ratn: not reported in source

    21-week-old Zucker diabetic fatty obese rats, cerebral blood vessels
    Comparator
    Lean control rats
    Outcome group
    Mitochondrial function · Metabolic and weight

    Source sentences

    Summary
    Levels of rattin, a rat humanin analog, tended to decrease in the diabetic group but did not reach statistical significance (P = 0.08).
    1 context sentence
    Summary · context
    Therefore, we investigated mitochondrial function and ROS production in cerebral blood vessels of 21-wk-old Zucker diabetic fatty obese rats and their lean controls.

    This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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