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Study · Non-randomized trial · n = 10 · 2019

4 results

Glucagon-like peptide-2 mobilizes lipids from the intestine by a systemic nitric oxide-independent mechanism.

Xiao C, Stahel P, Morgantini C, Nahmias A, Dash S, Lewis GF

Diabetes, obesity & metabolism19 Aug 2019Cited by 17 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In healthy male volunteers, teduglutide rapidly increased plasma triglyceride concentrations.

    In plain wordsIn healthy men, teduglutide rapidly increased blood triglycerides.

    Outcome
    IncreasePlasma triglycerides
    Study

    n = 10

    Outcome group
    Lipids · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Teduglutide rapidly increased mesenteric blood flow and TG concentrations in plasma, in TG-rich lipoproteins, and most robustly in chylomicrons.
  2. 02HumanNon-randomized trialEfficacy outcome

    In healthy male volunteers, teduglutide rapidly increased triglycerides in TG-rich lipoproteins.

    In plain wordsIn healthy men, teduglutide rapidly increased triglycerides in triglyceride-rich particles.

    Outcome
    IncreaseTG-rich lipoprotein triglycerides
    Study

    n = 10

    Outcome group
    Lipids · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Teduglutide rapidly increased mesenteric blood flow and TG concentrations in plasma, in TG-rich lipoproteins, and most robustly in chylomicrons.
  3. 03HumanNon-randomized trialEfficacy outcome

    In healthy male volunteers, teduglutide rapidly increased triglycerides most robustly in chylomicrons.

    In plain wordsIn healthy men, teduglutide increased triglycerides most strongly in chylomicrons.

    Outcome
    IncreaseChylomicron triglycerides
    Study

    n = 10

    Outcome group
    Lipids · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Teduglutide rapidly increased mesenteric blood flow and TG concentrations in plasma, in TG-rich lipoproteins, and most robustly in chylomicrons.
  4. 04HumanNon-randomized trialEfficacy outcome

    In healthy male volunteers, teduglutide rapidly increased mesenteric blood flow.

    In plain wordsIn healthy men, teduglutide rapidly increased blood flow to the intestine.

    Outcome
    IncreaseMesenteric blood flow
    Study

    n = 6

    Outcome group
    Vascular function · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Teduglutide rapidly increased mesenteric blood flow and TG concentrations in plasma, in TG-rich lipoproteins, and most robustly in chylomicrons.
    1 context sentence
    Summary · context
    TG in plasma and lipoprotein fractions were measured, along with measurement of blood flow in superior mesenteric and coeliac arteries using Doppler ultrasound in six participants.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:37 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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