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Study · Measured the body's own peptide · 2019

3 results

Protective Effect of Hyperbaric Oxygen Therapy on Cognitive Function in Patients with Vascular Dementia.

Xu Y, Wang Q, Qu Z, Yang J, Zhang X, Zhao Y

Cell transplantation28 May 2019Cited by 37 (Europe PMC)

PMID31134827 (opens in a new tab)PMCIDPMC6728711 (opens in a new tab)DOI10.1177/0963689719853540 (opens in a new tab)PepBankPUB-31134827
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelRandomized controlled trialOther

    In patients with vascular dementia, hyperbaric oxygen therapy increased serum humanin levels versus conventional treatment alone.

    In plain wordsIn people with vascular dementia, hyperbaric oxygen raised the body's own humanin levels in blood, compared with conventional treatment alone.

    Peptide
    Humanin
    Outcome
    IncreaseSerum humanin level after HBO therapy
    Study

    n = 158

    Comparator
    Control group with conventional treatment
    Outcome group
    Cognition and memory · Nervous system and cognition

    Source sentences

    Summary
    After treatment, compared with the control group, the MMSE scores and serum Humanin levels in the HBO group were significantly increased (p < 0.05).
    2 context sentences
    Summary · context
    A total of 158 patients with VD were prospectively included in the study and were randomly divided into control group and HBO group.
    Summary · context
    The control group was given conventional treatment and the HBO group was treated with HBO in addition to conventional treatment.

    This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelRandomized controlled trialOther

    In patients with vascular dementia, serum humanin levels were positively correlated with MMSE scores, independent of baseline characteristics.

    In plain wordsIn people with vascular dementia, higher natural humanin levels in blood were linked to higher memory test scores.

    Peptide
    Humanin
    Outcome
    Not applicableCorrelation of serum humanin with MMSE scores
    Study

    n = 158

    Outcome group
    Cognition and memory · Nervous system and cognition

    Measurements

    Spearman r
    0.409 r
    Serum humanin vs MMSE

    Source sentences

    Summary
    Spearman correlation analysis showed that the serum Humanin levels were positively correlated with MMSE scores (r = 0.409, p p < 0.05).
    2 context sentences
    Summary · context
    A total of 158 patients with VD were prospectively included in the study and were randomly divided into control group and HBO group.
    Summary · context
    The control group was given conventional treatment and the HBO group was treated with HBO in addition to conventional treatment.

    This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.

Studies that did not test the peptide alone1

In this study, Humanin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Humanin.

  1. 03HumanNot a test of Humanin aloneRandomized controlled trialEfficacy outcome

    In patients with vascular dementia, hyperbaric oxygen therapy increased MMSE scores versus conventional treatment alone.

    In plain wordsIn people with vascular dementia, hyperbaric oxygen improved memory test scores compared with conventional treatment alone. This result is about oxygen therapy, not humanin.

    Peptide
    Humanin
    Outcome
    IncreaseMMSE score after HBO therapy
    Study

    n = 158

    Comparator
    Control group with conventional treatment
    Outcome group
    Cognition and memory · Nervous system and cognition

    Source sentences

    Summary
    After treatment, compared with the control group, the MMSE scores and serum Humanin levels in the HBO group were significantly increased (p < 0.05).
    2 context sentences
    Summary · context
    A total of 158 patients with VD were prospectively included in the study and were randomly divided into control group and HBO group.
    Summary · context
    The control group was given conventional treatment and the HBO group was treated with HBO in addition to conventional treatment.

    In this study, Humanin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Humanin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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