In adults with obstructive sleep apnoea, a network meta-analysis found that nine pooled drugs, including liraglutide, significantly lowered the apnoea-hypopnoea-index compared with placebo.
In plain wordsIn adults with sleep apnoea, a review of trials found nine drugs together, liraglutide among them, lowered breathing pauses more than placebo.
- Peptide
- Liraglutide
- Outcome
- DecreaseApnoea-hypopnoea-index versus placebo
- Study
n: not reported in source
- Comparator
- Placebo
- Outcome group
- Sleep · Respiratory
Source sentences
In the network meta-analysis (I2 = 50%) nine drugs (tramazoline, liraglutide, spironolactone/furosemide, acetazolamide, dronabinol, zonisamide, phentermine, spironolactone, and ondansetron/fluoxetine) significantly lowered the AHI compared to placebo.
2 context sentences(design, population, supporting numbers)
According to a pre-registered study protocol (PROSPERO-ID-CRD42018086446) network meta-analysis was performed to obtain intervention effects on the apnoea-hypopnoea-index (AHI) based on data extracted from published reports.
We identified 58 RCTs (n = 1710 patients) investigating 44 different drugs or drug-combinations.
In this study, Liraglutide was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Liraglutide.