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Study · Not a test of the peptide alone · 2019

5 results

Quantification of controlled release leuprolide and triptorelin in rabbit plasma using electromembrane extraction coupled with HPLC-UV.

Hosseiny Davarani SS, Pourahadi A, Ghasemzadeh P

Electrophoresis30 Jan 2019Cited by 15 (Europe PMC)

PMID30653693 (opens in a new tab)DOI10.1002/elps.201800481 (opens in a new tab)PepBankPUB-30653693
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone5

In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  1. 01LabNot a test of Triptorelin (Trelstar, Decapeptyl) aloneIn vitro (cell-free)Activity measurement

    In rabbit plasma, the assay quantified triptorelin over 0.5-1000 ng/mL.

    In plain wordsIn lab tests, the assay quantified triptorelin over 0.5-1000 ng/mL.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableQuantification range
    Study

    rabbitn: not reported in source

    rabbit plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Quantification range
    0.5 to 1000 ng/mL
    rabbit plasma

    Source sentences

    Summary
    The range of quantification for both peptides was 0.5-1000 ng/mL with regression coefficients higher than 0.994.
    1 context sentence
    Summary · context
    An electromembrane extraction followed by HPLC-UV technique was developed and validated for quantification of leuprolide and triptorelin in rabbit plasma.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  2. 02LabNot a test of Triptorelin (Trelstar, Decapeptyl) aloneIn vitro (cell-free)Activity measurement

    In rabbit plasma, the triptorelin assay had regression coefficients higher than 0.994.

    In plain wordsIn lab tests, the triptorelin assay had regression coefficients higher than 0.994.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableRegression coefficient
    Study

    rabbitn: not reported in source

    rabbit plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    The range of quantification for both peptides was 0.5-1000 ng/mL with regression coefficients higher than 0.994.
    1 context sentence
    Summary · context
    An electromembrane extraction followed by HPLC-UV technique was developed and validated for quantification of leuprolide and triptorelin in rabbit plasma.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  3. 03LabNot a test of Triptorelin (Trelstar, Decapeptyl) aloneIn vitro (cell-free)Activity measurement

    In rabbit plasma, triptorelin relative recovery was 75.5%.

    In plain wordsIn lab tests, triptorelin recovery from rabbit plasma was 75.5%.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableRelative recovery
    Study

    rabbitn: not reported in source

    rabbit plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Relative recovery
    75.5%
    triptorelin

    Source sentences

    Summary
    Relative recoveries of leuprolide and triptorelin were found to be 80.3 and 75.5%, respectively.
    1 context sentence
    Summary · context
    An electromembrane extraction followed by HPLC-UV technique was developed and validated for quantification of leuprolide and triptorelin in rabbit plasma.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  4. 04LabNot a test of Triptorelin (Trelstar, Decapeptyl) aloneIn vitro (cell-free)Activity measurement

    In rabbit plasma, the triptorelin quantification limit was 0.5 ng/mL.

    In plain wordsIn lab tests, the triptorelin quantification limit was 0.5 ng/mL.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableLimit of quantification
    Study

    rabbitn: not reported in source

    rabbit plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Limit of quantification
    0.5 ng/mL
    triptorelin

    Source sentences

    Summary
    Limits of quantification and detection for both peptides were found to be 0.5 and 0.15 ng/mL, respectively.
    1 context sentence
    Summary · context
    An electromembrane extraction followed by HPLC-UV technique was developed and validated for quantification of leuprolide and triptorelin in rabbit plasma.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  5. 05LabNot a test of Triptorelin (Trelstar, Decapeptyl) aloneIn vitro (cell-free)Activity measurement

    In rabbit plasma, the triptorelin detection limit was 0.15 ng/mL.

    In plain wordsIn lab tests, the triptorelin detection limit was 0.15 ng/mL.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableLimit of detection
    Study

    rabbitn: not reported in source

    rabbit plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Limit of detection
    0.15 ng/mL
    triptorelin

    Source sentences

    Summary
    Limits of quantification and detection for both peptides were found to be 0.5 and 0.15 ng/mL, respectively.
    1 context sentence
    Summary · context
    An electromembrane extraction followed by HPLC-UV technique was developed and validated for quantification of leuprolide and triptorelin in rabbit plasma.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    27 Oct 2026, 16:37 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    22 Oct 2026, 02:26 UTC

    Study results updated

  3. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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