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Study · Non-randomized trial · 2019

3 results

Age-dependent changes in the reproductive axis responsiveness to kisspeptin-10 administration in healthy men.

Ullah H, Nabi G, Zubair H, Ullah R, Shahab M

Andrologia27 Dec 2018Cited by 9 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In healthy adult, middle-aged and advanced-age men, a single intravenous bolus of kisspeptin‑10 significantly increased plasma LH in all age groups.

    In plain wordsIn healthy men of all ages, kisspeptin‑10 raised blood LH levels after one injection.

    Outcome
    IncreasePlasma LH after kisspeptin-10
    Study

    n: not reported in source

    Comparator
    Pre-injection baseline
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    1 µg/kg BW · intravenous · single bolusAs given in this study (human).

    Source sentences

    Summary
    Analysis of plasma LH by ELISA showed a significant (p < 0.05) increase after kisspeptin-10 administration in all groups
    1 context sentence
    Summary · context
    Human kisspeptin-10 was administered in single iv bolus dose (1 µg/kg BW) to healthy adult, middle and advanced age men.
  2. 02HumanNon-randomized trialEfficacy outcome

    In healthy adult men, a single intravenous bolus of kisspeptin‑10 significantly increased plasma testosterone.

    In plain wordsIn healthy adult men, kisspeptin‑10 raised blood testosterone after one injection.

    Outcome
    IncreasePlasma testosterone in adult men
    Study

    n: not reported in source

    Comparator
    Pre-injection baseline
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    1 µg/kg BW · intravenous · single bolusAs given in this study (human).

    Source sentences

    Summary
    whereas plasma testosterone concentration was significantly elevated (p < 0.05) after kisspeptin-10 injection only in the adult men group.
    1 context sentence
    Summary · context
    Human kisspeptin-10 was administered in single iv bolus dose (1 µg/kg BW) to healthy adult, middle and advanced age men.
  3. 03HumanNon-randomized trialEfficacy outcome

    In middle-aged and advanced-age men, plasma testosterone did not rise significantly after kisspeptin‑10, which rose only in the adult group.

    In plain wordsIn middle-aged and older men, kisspeptin‑10 did not raise blood testosterone, unlike in younger adult men.

    Outcome
    No significant changePlasma testosterone in middle-aged and advanced-age men
    Study

    n: not reported in source

    Comparator
    Pre-injection baseline
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    1 µg/kg BW · intravenous · single bolusAs given in this study (human).

    Source sentences

    Summary
    whereas plasma testosterone concentration was significantly elevated (p < 0.05) after kisspeptin-10 injection only in the adult men group.
    1 context sentence
    Summary · context
    Human kisspeptin-10 was administered in single iv bolus dose (1 µg/kg BW) to healthy adult, middle and advanced age men.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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