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Study · Not a test of the peptide alone · 2018

2 results

Thymosin-β4 Mediates Hepatic Stellate Cell Activation by Interfering with CircRNA-0067835/miR-155/FoxO3 Signaling Pathway.

Zhu L, Ren T, Zhu Z, Cheng M, Mou Q, Mu M, Liu Y, Yao Y, Cheng Y, Zhang B, Cheng Z

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology27 Nov 2018Cited by 48 (Europe PMC)

PMID30481761 (opens in a new tab)DOI10.1159/000495556 (opens in a new tab)PepBankPUB-30481761
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 01LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cells)Mechanism

    In LX-2 hepatic stellate cells, thymosin beta‑4 depletion changed the expression of 644 circRNAs compared with control cells.

    In plain wordsIn liver scar-forming cells, removing thymosin beta‑4 changed the levels of 644 circular RNAs compared with control cells.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableDifferentially expressed circRNAs after thymosin beta-4 depletion
    Study

    n: not reported in source

    LX-2 hepatic stellate cells
    Comparator
    Control LX-2 cells
    Outcome group
    Receptor activity and mechanism · Liver

    Source sentences

    Summary
    A total of 644 differentially expressed circRNAs were identified between the Tβ4-depleted LX-2 cells and the control LX2 cells.
    1 context sentence
    Summary · context
    Circular RNA microarray was conducted to identify Tβ4-related circRNAs.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  2. 02LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cells)Mechanism

    In LX-2 hepatic stellate cells, circRNA-0067835 expression was significantly higher after thymosin beta‑4 depletion than in control cells.

    In plain wordsIn liver scar-forming cells, removing thymosin beta‑4 raised the level of one circular RNA compared with control cells.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreasecircRNA-0067835 expression after thymosin beta-4 depletion
    Study

    n: not reported in source

    LX-2 hepatic stellate cells
    Comparator
    Control LX-2 cells
    Outcome group
    Receptor activity and mechanism · Liver

    Source sentences

    Summary
    The expression of circRNA-0067835 was significantly increased in the Tβ4-depleted LX-2 cells compared with control.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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