In pre-pubertal bitches given deslorelin or placebo implants, kisspeptin‑10 expression in uterine tissue was low in all cell types and highest in vascular endothelial cells.
In plain wordsIn dogs, the body's own kisspeptin‑10 in the uterus was low in all cell types and highest in blood vessel lining cells.
- Peptide
- Kisspeptin-10
- Outcome
- Not applicableKisspeptin-10 expression in uterine tissue
- Study
dogn = 11
Uterine tissue, immunohistochemistry- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
Source sentences
Kisspeptin 10 expression was low in all cell types, highest IRS were seen in the vascular endothelial cells.
2 context sentences(design, population, supporting numbers)
Aim of the study was to examine the effect of deslorelin on uterine tissues of eleven pre-pubertal bitches aged 4.2 ± 0.6 m.
Bitches were ovariohysterectomized and sections from the uterine tissue were subjected to immunohistochemistry (IHC) for detection of GnRH receptor (R), Kisspeptin (KP)10, Kisspeptin receptor (GPR54), androgen receptor (AR), oestrogen receptor (ER) α,β, and progesterone receptor (PR).
This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.