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Study · In vitro (cells) · 2019

2 results

Characterization of a third ghrelin receptor, GHS-R3a, in channel catfish reveals novel expression patterns and a high affinity for homologous ligand.

Small BC, Quiniou SMA, Kaiya H, Bledsoe JW, Musungu B

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology22 Nov 2018Cited by 4 (Europe PMC)

PMID30471349 (opens in a new tab)DOI10.1016/j.cbpa.2018.11.013 (opens in a new tab)PepBankPUB-30471349
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In HEK 293 cells expressing catfish GHS-R3a, GHRP‑6 did not change the intracellular Ca2+ concentration.

    In plain wordsIn cells carrying the catfish GHS-R3a receptor, GHRP‑6 did not change calcium levels inside the cells.

    Peptide
    GHRP-6
    Outcome
    No significant changeIntracellular Ca2+ concentration
    Study

    humann: not reported in source

    HEK 293 cells stably expressing channel catfish GHS-R3a
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    On the contrary, intracellular Ca2+ concentration was unaffected by treatment with the synthetic growth hormone secretagogues GHRP-6 and hexarelin.
    1 context sentence
    Summary · context
    In functional analyses, homologous catfish ghrelin increased intracellular Ca2+ concentration in human embryonic kidney (HEK) 293 cells stably expressing catfish GHS-R3a.
  2. 02LabIn vitro (cells)Activity measurement

    In HEK 293 cells expressing catfish GHS-R3a, hexarelin did not change the intracellular Ca2+ concentration.

    In plain wordsIn cells carrying the catfish GHS-R3a receptor, hexarelin did not change calcium levels inside the cells.

    Peptide
    Hexarelin
    Outcome
    No significant changeIntracellular Ca2+ concentration
    Study

    humann: not reported in source

    HEK 293 cells stably expressing channel catfish GHS-R3a
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    On the contrary, intracellular Ca2+ concentration was unaffected by treatment with the synthetic growth hormone secretagogues GHRP-6 and hexarelin.
    1 context sentence
    Summary · context
    In functional analyses, homologous catfish ghrelin increased intracellular Ca2+ concentration in human embryonic kidney (HEK) 293 cells stably expressing catfish GHS-R3a.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 2

    13 Oct 2026, 16:31 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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