[The role of the combined balneotherapeutic treatment as the 'add-back therapy' against the background of the anti-hormonal effects of the agonists of gonadotropin-releasing hormone in the women suffering from endometriosis genitalis externa].

Akhkubekova NK, Kaysinova AS, Fedorov AA, Efimenko NB, Gaidamaka II, Chalaja EN, Cherevashchenko LA, Tsallagova LV, Urvacheva EE, Ovsienko AB

Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury1 Jan 2018

PMID30412147DOI10.17116/kurort20189505131PepBankPUB-30412147

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone7

In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Triptorelin (Trelstar, Decapeptyl).

01HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneRandomized controlled trialEfficacy outcome
After endometriosis surgery, ovarian endometriosis recurrence was 2.5% with mineral water, radon and triptorelin versus 7.5% with triptorelin alone.
In plain wordsAfter endometriosis surgery, recurrence was 2.5% with mineral water, radon and triptorelin versus 7.5% with triptorelin alone.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseOvarian endometriosis recurrence
Study
n: not reported in source
Comparator
Triptorelin alone
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Measurements
Recurrence
2.5%
spa therapy plus triptorelin
Recurrence
7.5%
triptorelin alone
Source sentences
Summary
specifically, only 2.5% of the patients suffered the recurrence of cystic ovarian endometriosis whereas 24.5% (p<0.001) reported the restoration of the reproductive function.
2 context sentences(design, population, supporting numbers)
Summary · context
The patients comprising the control group experienced the recurrence of the pathologic process in 7.5% of the cases and the restoration of the reproductive function in 15.8% of the cases (p<0.001).
Summary · context
The main group (MG) was comprised of 45 women received medical rehabilitation under conditions of a spa and health resort setting with the application of medium-salt water from the Pyatigorsk spring and radon therapy in the combination with triptorelin. The group of comparison (CG) was composed of 4…
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-3041214701
02HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneRandomized controlled trialEfficacy outcome
After endometriosis surgery, reproductive function returned in 24.5% with mineral water, radon and triptorelin versus 15.8% with triptorelin alone.
In plain wordsAfter endometriosis surgery, reproductive function returned in 24.5% with mineral water, radon and triptorelin versus 15.8% with triptorelin alone.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
IncreaseRestoration of reproductive function
Study
n: not reported in source
Comparator
Triptorelin alone
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Measurements
Restoration of reproductive function
24.5%
spa therapy plus triptorelin
Restoration of reproductive function
15.8%
triptorelin alone
Source sentences
Summary
specifically, only 2.5% of the patients suffered the recurrence of cystic ovarian endometriosis whereas 24.5% (p<0.001) reported the restoration of the reproductive function.
2 context sentences(design, population, supporting numbers)
Summary · context
The patients comprising the control group experienced the recurrence of the pathologic process in 7.5% of the cases and the restoration of the reproductive function in 15.8% of the cases (p<0.001).
Summary · context
The main group (MG) was comprised of 45 women received medical rehabilitation under conditions of a spa and health resort setting with the application of medium-salt water from the Pyatigorsk spring and radon therapy in the combination with triptorelin. The group of comparison (CG) was composed of 4…
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-3041214702
03HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneRandomized controlled trialEfficacy outcome
In women after endometriosis surgery, quality of life improved 3.4 times from baseline with mineral water, radon therapy and triptorelin, and 2.2-fold with triptorelin alone.
In plain wordsAfter endometriosis surgery, quality of life improved from baseline with mineral water, radon therapy and triptorelin, and also with triptorelin alone.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
IncreaseQuality of life
Study
n: not reported in source
Comparator
Initial level
Outcome group
Quality of life · Reproductive and sexual health
Measurements
Quality of life improvement
3.4 fold
spa therapy plus triptorelin versus baseline
Quality of life improvement
2.2 fold
triptorelin alone versus baseline
Source sentences
Summary
Simultaneously, the quality of life in the patients in the main group improved 3.4 times on the average in comparison with the initial level (p<0.001).
Summary
The 2.2-fold improvement of the quality of life was documented in the control patients (p<0.001).
2 context sentences(design, population, supporting numbers)
Summary · context
The main group (MG) was comprised of 45 women received medical rehabilitation under conditions of a spa and health resort setting with the application of medium-salt water from the Pyatigorsk spring and radon therapy in the combination with triptorelin.
Summary · context
The group of comparison (CG) was composed of 44 women given the treatment with the use of triptorelin under the out-patient conditions.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-3041214703
04HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneRandomized controlled trialSafety outcome
In women after endometriosis surgery, epigastric pain was less frequent with spa therapy plus triptorelin than triptorelin alone.
In plain wordsAfter endometriosis surgery, epigastric pain was less frequent with spa therapy plus triptorelin than triptorelin alone.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseEpigastric pain
Study
n: not reported in source
Comparator
Triptorelin alone
Outcome group
Adverse events · Reproductive and sexual health
Source sentences
Summary
At the same time, the frequency of adverse reactions to the treatment with triptorelin in the control patients was higher than in the main group including pain in the epigastric area, headache, irritability, hyperhidrosis, and instability of arterial blood pressure (ABP) that significantly deteriora…
2 context sentences(design, population, supporting numbers)
Summary · context
The main group (MG) was comprised of 45 women received medical rehabilitation under conditions of a spa and health resort setting with the application of medium-salt water from the Pyatigorsk spring and radon therapy in the combination with triptorelin.
Summary · context
The group of comparison (CG) was composed of 44 women given the treatment with the use of triptorelin under the out-patient conditions.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-3041214704
05HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneRandomized controlled trialSafety outcome
In women after endometriosis surgery, headache was less frequent with spa therapy plus triptorelin than triptorelin alone.
In plain wordsAfter endometriosis surgery, headache was less frequent with spa therapy plus triptorelin than triptorelin alone.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseHeadache
Study
n: not reported in source
Comparator
Triptorelin alone
Outcome group
Adverse events · Reproductive and sexual health
Source sentences
Summary
At the same time, the frequency of adverse reactions to the treatment with triptorelin in the control patients was higher than in the main group including pain in the epigastric area, headache, irritability, hyperhidrosis, and instability of arterial blood pressure (ABP) that significantly deteriora…
2 context sentences(design, population, supporting numbers)
Summary · context
The main group (MG) was comprised of 45 women received medical rehabilitation under conditions of a spa and health resort setting with the application of medium-salt water from the Pyatigorsk spring and radon therapy in the combination with triptorelin.
Summary · context
The group of comparison (CG) was composed of 44 women given the treatment with the use of triptorelin under the out-patient conditions.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-3041214705
06HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneRandomized controlled trialSafety outcome
In women after endometriosis surgery, irritability was less frequent with spa therapy plus triptorelin than triptorelin alone.
In plain wordsAfter endometriosis surgery, irritability was less frequent with spa therapy plus triptorelin than triptorelin alone.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseIrritability
Study
n: not reported in source
Comparator
Triptorelin alone
Outcome group
Adverse events · Reproductive and sexual health
Source sentences
Summary
At the same time, the frequency of adverse reactions to the treatment with triptorelin in the control patients was higher than in the main group including pain in the epigastric area, headache, irritability, hyperhidrosis, and instability of arterial blood pressure (ABP) that significantly deteriora…
2 context sentences(design, population, supporting numbers)
Summary · context
The main group (MG) was comprised of 45 women received medical rehabilitation under conditions of a spa and health resort setting with the application of medium-salt water from the Pyatigorsk spring and radon therapy in the combination with triptorelin.
Summary · context
The group of comparison (CG) was composed of 44 women given the treatment with the use of triptorelin under the out-patient conditions.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-3041214706
07HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneRandomized controlled trialSafety outcome
In women after endometriosis surgery, adverse reactions to triptorelin (epigastric pain, headache, irritability, hyperhidrosis, blood pressure instability) were less frequent with spa therapy plus triptorelin than with triptorelin alone.
In plain wordsAfter endometriosis surgery, side effects of triptorelin were less frequent with spa therapy plus triptorelin than with triptorelin alone.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseAdverse reactions to triptorelin
Study
n: not reported in source
Comparator
Triptorelin alone
Outcome group
Adverse events · Reproductive and sexual health
Source sentences
Summary
At the same time, the frequency of adverse reactions to the treatment with triptorelin in the control patients was higher than in the main group including pain in the epigastric area, headache, irritability, hyperhidrosis, and instability of arterial blood pressure (ABP) that significantly deteriora…
2 context sentences(design, population, supporting numbers)
Summary · context
The main group (MG) was comprised of 45 women received medical rehabilitation under conditions of a spa and health resort setting with the application of medium-salt water from the Pyatigorsk spring and radon therapy in the combination with triptorelin.
Summary · context
The group of comparison (CG) was composed of 44 women given the treatment with the use of triptorelin under the out-patient conditions.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-3041214707

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
22 Oct 2026, 02:26 UTC
Study results updated
Version 1
21 Oct 2026, 18:59 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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MeSH terms

Keywords

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