In mice infected with Plasmodium berghei ANKA, the body's own thymosin beta‑4 expression in the liver was significantly higher than in control mice.
In plain wordsIn malaria-infected mice, the body's own thymosin beta‑4 in the liver was higher than in uninfected mice.
- Peptide
- Thymosin beta-4 (human)
- Outcome
- IncreaseHepatic thymosin beta-4 expression in malaria-infected mice
- Study
mousen: not reported in source
Plasmodium berghei ANKA infection- Comparator
- Uninfected control mice
- Outcome group
- Liver fat and liver function · Liver
Source sentences
Expression of fibrotic markers, including transforming growth factor-β, α-smooth muscle actin (α-SMA), collagen 1a1, thymosin β4, and vimentin, were significantly higher in the infected groups than in the control group.
1 context sentence(design, population, supporting numbers)
Eight-week-old male C57BL/6 mice inoculated with blood containing Plasmodium berghei ANKA (PbA)-infected erythrocytes were sacrificed when the level of parasitemia in the blood reached 10% or 30%, and the livers were collected for biochemical analysis.
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.