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Study · Animal study (in vivo) · rat · 2018

2 results

Gonadotropin-releasing hormone and kisseptin-10 regulate nuclear receptor subfamily 5 group a member 1/catenin beta 1/ nuclear receptor subfamily 0 group B member 1 activity in female rat anterior pituitary gland.

Zielinska-Gorska M, Gorski K, Biernacka K, Sawosy E, Kaminska T, Gajewska A

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society1 Jun 2018Cited by 1 (Europe PMC)

PMID30342431 (opens in a new tab)DOI10.26402/jpp.2018.3.14 (opens in a new tab)PepBankPUB-30342431
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In ovariectomized rats, kisspeptin‑10 infusion into the third ventricle up-regulated Nr0b1 mRNA expression in the anterior pituitary.

    In plain wordsIn rats, kisspeptin‑10 given into the brain raised Nr0b1 gene activity in the pituitary gland.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseNr0b1 mRNA expression in anterior pituitary
    Study

    ratn: not reported in source

    Ovariectomized female rats, anterior pituitary
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    Dose not stated · into the third ventricleAs given in this study (rat).

    Source sentences

    Summary
    After kisspeptin-10 treatment, up-regulation of Nr0b1 mRNA and protein expression in the anterior pituitary was observed.
    1 context sentence
    Summary · context
    Adult ovariectomized rats were given a serial infusion of Gnrh, kisspeptin-10, Gnrh + Gnrh antagonist (Antide), or kisspeptin-10 + kisspeptin antagonist (kisspeptin-234) into the third ventricle of the brain.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In ovariectomized rats, kisspeptin‑10 infusion into the third ventricle up-regulated Nr0b1 protein expression in the anterior pituitary.

    In plain wordsIn rats, kisspeptin‑10 given into the brain raised the amount of Nr0b1 protein in the pituitary gland.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseNR0B1 protein expression in anterior pituitary
    Study

    ratn: not reported in source

    Ovariectomized female rats, anterior pituitary
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    Dose not stated · into the third ventricleAs given in this study (rat).

    Source sentences

    Summary
    After kisspeptin-10 treatment, up-regulation of Nr0b1 mRNA and protein expression in the anterior pituitary was observed.
    1 context sentence
    Summary · context
    Adult ovariectomized rats were given a serial infusion of Gnrh, kisspeptin-10, Gnrh + Gnrh antagonist (Antide), or kisspeptin-10 + kisspeptin antagonist (kisspeptin-234) into the third ventricle of the brain.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

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