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Study · Non-randomized trial · n = 62 · 2018

3 results

[Efficacy of Korteksin in acute period of hemispheric ischemic stroke].

Belova LA, Mashin VV, Abramova VV, Slastyon EY, Belov DV

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova1 Jan 2018Cited by 2 (Europe PMC)

PMID30132453 (opens in a new tab)DOI10.17116/jnevro20181187130 (opens in a new tab)PepBankPUB-30132453
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In acute hemispheric ischemic stroke, two courses of cortexin 30 mg daily (10+10+10) reduced neurological deficit more completely than cortexin 20 mg with basic therapy (group 1).

    In plain wordsIn acute stroke, neurological deficit regressed more completely with two courses of cortexin 30 mg than with cortexin 20 mg in group 1.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    DecreaseRegression of neurological deficit
    Study

    n = 62

    Comparator
    Cortexin 20 mg with basic therapy, first group
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    30 mg daily (10+10+10) · Two 10-day courses separated by 10 daysAs given in this study (human).

    Source sentences

    Summary
    The most complete regression of neurological deficit during the acute period of ischemic stroke was observed in the fourth group of patients (30 mg (10+10+10) of cortexin, two courses) compared to the 1-3 groups.
    2 context sentences
    Summary · context
    Patients of the first group (n=30) received cortexin in a dose of 20 mg (10+10) intramuscularly along with basic therapy,
    Summary · context
    One hundred and twenty-two patients with hemispheric ischemic stroke were studied.
  2. 02HumanNon-randomized trialEfficacy outcome

    In acute hemispheric ischemic stroke, two courses of cortexin 30 mg daily (10+10+10) reduced neurological deficit more completely than two courses of cortexin 20 mg.

    In plain wordsIn acute stroke, neurological deficit regressed more completely with two courses of cortexin 30 mg than with two courses of 20 mg.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    DecreaseRegression of neurological deficit
    Study

    n = 62

    Comparator
    Two Cortexin 20 mg courses, second group
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    30 mg daily (10+10+10) · Two 10-day courses separated by 10 daysAs given in this study (human).

    Source sentences

    Summary
    The most complete regression of neurological deficit during the acute period of ischemic stroke was observed in the fourth group of patients (30 mg (10+10+10) of cortexin, two courses) compared to the 1-3 groups.
    2 context sentences
    Summary · context
    patients of the second group (n=30) received two courses of cortexin in the same dose for 10 days each with a break of 10 days in-between,
    Summary · context
    One hundred and twenty-two patients with hemispheric ischemic stroke were studied.
  3. 03HumanNon-randomized trialEfficacy outcome

    In hemispheric ischemic stroke, two Cortexin courses at 30 mg daily reduced neurological deficit more completely than basic therapy alone.

    In plain wordsIn hemispheric ischemic stroke, neurological deficit regressed more completely with two Cortexin courses at 30 mg than with basic therapy alone.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    DecreaseRegression of neurological deficit
    Study

    n = 62

    Comparator
    Basic therapy only
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    30 mg daily (10+10+10) · Two 10-day courses separated by 10 daysAs given in this study (human).

    Source sentences

    Summary
    The most complete regression of neurological deficit during the acute period of ischemic stroke was observed in the fourth group of patients (30 mg (10+10+10) of cortexin, two courses) compared to the 1-3 groups.
    2 context sentences
    Summary · context
    patients of the third group (n=30) received only basic therapy,
    Summary · context
    One hundred and twenty-two patients with hemispheric ischemic stroke were studied.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:25 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

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