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Study · In vitro (cells) · rat · 2018

2 results

Kisspeptin increases intracellular calcium concentration by protein kinase C-mediated signaling in the primary cultured neurons from rat hippocampus.

Serhatlioglu I, Yuksel H, Kacar E, Ozcan S, Canpolat S, Ozcan M, Ayar A, Kelestimur H

Cellular and molecular biology (Noisy-le-Grand, France)30 May 2018Cited by 1 (Europe PMC)

PMID29974847 (opens in a new tab)DOI10.14715/cmb/2018.64.7.10 (opens in a new tab)PepBankPUB-29974847
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In primary rat hippocampal neurons, kisspeptin‑10 caused transient increases in intracellular calcium.

    In plain wordsIn cells from rat brain, kisspeptin‑10 caused short rises in calcium inside neurons.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseIntracellular calcium transients
    Study

    ratn: not reported in source

    Primary cultured hippocampal neurons
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Kisspeptin-10 caused [Ca2+]i transients in hippocampal neurons.
    1 context sentence
    Summary · context
    The influences of kisspeptin on [Ca2+]i in hippocampal neurons were examined through in vitro calcium imaging system.
  2. 02LabIn vitro (cells)Mechanism

    In primary rat hippocampal neurons, the change in intracellular calcium by 100 nM kisspeptin was prevented by pre-treatment with the PKC inhibitor chelerythrine chloride.

    In plain wordsIn cells from rat brain, a PKC blocker stopped the calcium change that kisspeptin caused.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableCalcium change by kisspeptin with PKC inhibitor
    Study

    ratn: not reported in source

    Primary cultured hippocampal neurons
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    100 nMAs given in this study (rat).

    Source sentences

    Summary
    The change in [Ca2+]i by 100 nM kisspeptin was prevented by pre-treating the cells in PKC inhibitor chelerythrine chloride.
    1 context sentence
    Summary · context
    The influences of kisspeptin on [Ca2+]i in hippocampal neurons were examined through in vitro calcium imaging system.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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