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Study · Not a test of the peptide alone · 2018

2 results

Cognitive benefits of angiotensin IV and angiotensin-(1-7): A systematic review of experimental studies.

Ho JK, Nation DA

Neuroscience and biobehavioral reviews4 May 2018Cited by 42 (Europe PMC)

PMID29733881 (opens in a new tab)PMCIDPMC8916541 (opens in a new tab)DOI10.1016/j.neubiorev.2018.05.005 (opens in a new tab)PepBankPUB-29733881
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Dihexa was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Dihexa.

  1. 01AnimalNot a test of Dihexa aloneAnimal study (in vivo)Efficacy outcome

    In animal models of cognitive deficit, pooled Ang IV and analog studies, including dihexa, reported improved spatial working memory performance.

    In plain wordsIn animals with cognitive deficits, pooled Ang IV and analog studies, including dihexa, reported improved spatial working memory.

    Peptide
    Dihexa
    Outcome
    IncreaseSpatial working memory performance
    Study

    n: not reported in source

    Animal models of cognitive deficit
    Outcome group
    Cognition and memory · Nervous system and cognition

    Source sentences

    Summary
    In models of cognitive deficit, eight of nine studies found Ang IV and its analogs (Nle1-Ang IV, dihexa, LVV-hemorphin-7) improved performance on spatial working memory and passive avoidance tasks.
    1 context sentence
    Summary · context
    Systematic review of experimental (non-human) studies assessing cognitive effects of RAS peptides angiotensin-(3-8) [Ang IV] and angiotensin-(1-7) [Ang-(1-7)] and their receptors, the Ang IV receptor (AT4R) and the Mas receptor.

    In this study, Dihexa was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Dihexa.

  2. 02AnimalNot a test of Dihexa aloneAnimal study (in vivo)Efficacy outcome

    In animal models of cognitive deficit, pooled Ang IV and analog studies, including dihexa, reported improved passive avoidance performance.

    In plain wordsIn animals with cognitive deficits, pooled Ang IV and analog studies, including dihexa, reported improved passive avoidance performance.

    Peptide
    Dihexa
    Outcome
    IncreasePassive avoidance performance
    Study

    n: not reported in source

    Animal models of cognitive deficit
    Outcome group
    Cognition and memory · Nervous system and cognition

    Source sentences

    Summary
    In models of cognitive deficit, eight of nine studies found Ang IV and its analogs (Nle1-Ang IV, dihexa, LVV-hemorphin-7) improved performance on spatial working memory and passive avoidance tasks.
    1 context sentence
    Summary · context
    Systematic review of experimental (non-human) studies assessing cognitive effects of RAS peptides angiotensin-(3-8) [Ang IV] and angiotensin-(1-7) [Ang-(1-7)] and their receptors, the Ang IV receptor (AT4R) and the Mas receptor.

    In this study, Dihexa was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Dihexa.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:45 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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