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Study · Not a test of the peptide alone · 2018

4 results

Multi-omics analysis identifies pathways and genes involved in diffuse-type gastric carcinogenesis induced by E-cadherin, p53, and Smad4 loss in mice.

Park JW, Kim MS, Voon DC, Kim SJ, Bae J, Mun DG, Ko SI, Kim HK, Lee SW, Kim DY

Molecular carcinogenesis30 Mar 2018Cited by 17 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 01LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cells)Mechanism

    In diffuse-type gastric cancer cells, Tβ4 suppressed E-cadherin expression.

    In plain wordsIn cancer cells, Tβ4 lowered the amount of E-cadherin, a protein that holds cells together.

    Outcome
    DecreaseE-cadherin expression
    Study

    n: not reported in source

    diffuse-type gastric cancer cells
    Outcome group
    Tumor growth · Cancer

    Source sentences

    Summary
    Specifically, Tβ4 suppressed E-cadherin expression and anoikis while promoting cancer cell growth and migration.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  2. 02LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cells)Mechanism

    In diffuse-type gastric cancer cells, Tβ4 suppressed anoikis.

    In plain wordsIn cancer cells, Tβ4 reduced a type of cell death that follows loss of cell attachment.

    Outcome
    DecreaseAnoikis
    Study

    n: not reported in source

    diffuse-type gastric cancer cells
    Outcome group
    Tumor growth · Cancer

    Source sentences

    Summary
    Specifically, Tβ4 suppressed E-cadherin expression and anoikis while promoting cancer cell growth and migration.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  3. 03LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cells)Mechanism

    In diffuse-type gastric cancer cells, Tβ4 promoted cancer cell growth.

    In plain wordsIn cancer cells, Tβ4 increased cell growth.

    Outcome
    IncreaseCancer cell growth
    Study

    n: not reported in source

    diffuse-type gastric cancer cells
    Outcome group
    Tumor growth · Cancer

    Source sentences

    Summary
    Specifically, Tβ4 suppressed E-cadherin expression and anoikis while promoting cancer cell growth and migration.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  4. 04LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cells)Mechanism

    In diffuse-type gastric cancer cells, Tβ4 promoted cancer cell migration.

    In plain wordsIn cancer cells, Tβ4 increased cell movement.

    Outcome
    IncreaseCancer cell migration
    Study

    n: not reported in source

    diffuse-type gastric cancer cells
    Outcome group
    Cancer cell invasion and metastasis · Cancer

    Source sentences

    Summary
    Specifically, Tβ4 suppressed E-cadherin expression and anoikis while promoting cancer cell growth and migration.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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