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Study · Randomized controlled trial · n = 40 · 2017

5 results

Comparison of two different dosage of GnRH agonist as ovulation trigger in oocyte donors: a randomized controled trial.

Zarcos SM, Mejía PV, Stefani CD, Martin PS, Martin FS

JBRA assisted reproduction1 Sept 2017Cited by 8 (Europe PMC)

PMID28837025 (opens in a new tab)PMCIDPMC5574638 (opens in a new tab)DOI10.5935/1518-0557.20170036 (opens in a new tab)PepBankPUB-28837025
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. 5 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In oocyte donors, mean total oocyte yield was 16 with triptorelin 0.3 mg versus 15 with 0.4 mg, and the summary reports no group difference for this count.

    In plain wordsIn oocyte donors, the 0.3 mg and 0.4 mg triptorelin doses gave similar total oocyte counts (16 versus 15).

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeTotal collected oocytes
    Study

    n = 40

    Comparator
    Triptorelin 0.4 mg
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.3 mgAs given in this study (human).

    Measurements

    Mean total collected oocytes
    16 oocytes
    0.3mg
    Mean total collected oocytes
    15 oocytes
    0.4mg

    Source sentences

    Summary
    The average of total collected oocytes were 16 (Group A) versus 15 (Group B), and the mean number of mature oocytes were 13 versus 12 respectively.
    3 context sentences
    Summary · context
    Experimental controlled randomized trial including 40 patients from a private practice center.
    Summary · context
    Group A received a single dose of Triptorelin 0.3mg (Decapeptyl®) 36hours before pick-up.
    Summary · context
    Group B patients received Triptorelin 0.4mg (Decapeptyl®) before pick-up to final oocyte maturation.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In oocyte donors, mean mature oocyte yield was 13 with triptorelin 0.3 mg versus 12 with 0.4 mg, and the summary reports no group difference for this count.

    In plain wordsIn oocyte donors, the 0.3 mg and 0.4 mg triptorelin doses gave similar mature oocyte counts (13 versus 12).

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeMature oocyte count
    Study

    n = 40

    Comparator
    Triptorelin 0.4 mg
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.3 mgAs given in this study (human).

    Measurements

    Mean mature oocytes
    13 oocytes
    0.3mg
    Mean mature oocytes
    12 oocytes
    0.4mg

    Source sentences

    Summary
    The average of total collected oocytes were 16 (Group A) versus 15 (Group B), and the mean number of mature oocytes were 13 versus 12 respectively.
    3 context sentences
    Summary · context
    Experimental controlled randomized trial including 40 patients from a private practice center.
    Summary · context
    Group A received a single dose of Triptorelin 0.3mg (Decapeptyl®) 36hours before pick-up.
    Summary · context
    Group B patients received Triptorelin 0.4mg (Decapeptyl®) before pick-up to final oocyte maturation.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In oocyte donors, mature oocyte percentage did not differ significantly between triptorelin doses.

    In plain wordsIn oocyte donors, mature oocyte percentages did not differ significantly between triptorelin doses.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeMature oocyte percentage
    Study

    n = 40

    Comparator
    Triptorelin 0.4 mg
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.3 mgAs given in this study (human).

    Measurements

    Mature oocytes
    84.6%
    0.3mg
    Mature oocytes
    78.6%
    0.4mg

    Source sentences

    Summary
    The only variable showing a difference was the percentage of mature oocytes, which was greater in Group A, resulting in 84.6%, in contrast with those treated with 0.4mg of Triptorelin (78.6%), although these differences were not statistical significant (p=0.35).
    3 context sentences
    Summary · context
    Experimental controlled randomized trial including 40 patients from a private practice center.
    Summary · context
    Group A received a single dose of Triptorelin 0.3mg (Decapeptyl®) 36hours before pick-up.
    Summary · context
    Group B patients received Triptorelin 0.4mg (Decapeptyl®) before pick-up to final oocyte maturation.
  4. 04HumanRandomized controlled trialEfficacy outcome

    In oocyte donors, stimulation duration did not differ between triptorelin doses.

    In plain wordsIn oocyte donors, stimulation duration did not differ significantly between the two triptorelin doses.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeStimulation duration
    Study

    n = 40

    Comparator
    Triptorelin 0.4 mg
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    0.3 mgAs given in this study (human).

    Source sentences

    Summary
    Days of stimulation did not differ between groups.
    3 context sentences
    Summary · context
    Experimental controlled randomized trial including 40 patients from a private practice center.
    Summary · context
    Group A received a single dose of Triptorelin 0.3mg (Decapeptyl®) 36hours before pick-up.
    Summary · context
    Group B patients received Triptorelin 0.4mg (Decapeptyl®) before pick-up to final oocyte maturation.
  5. 05HumanRandomized controlled trialSafety outcome

    In oocyte donors receiving triptorelin, no empty follicle syndrome cases were reported.

    In plain wordsIn oocyte donors receiving triptorelin, no empty follicle syndrome cases occurred.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableEmpty follicle syndrome
    Study

    n = 40

    Outcome group
    Adverse events · Reproductive and sexual health
    Studied dose
    0.3 or 0.4 mgAs given in this study (human).

    Source sentences

    Summary
    No cases of empty follicle syndrome were reported.
    3 context sentences
    Summary · context
    Experimental controlled randomized trial including 40 patients from a private practice center.
    Summary · context
    Group A received a single dose of Triptorelin 0.3mg (Decapeptyl®) 36hours before pick-up.
    Summary · context
    Group B patients received Triptorelin 0.4mg (Decapeptyl®) before pick-up to final oocyte maturation.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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