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Study · Animal study (in vivo) · pig · 2017

7 results

Effects of estrus synchronization using Matrix® followed by treatment with the GnRH agonist triptorelin to control ovulation in mature gilts.

Knox RV, Webel SK, Swanson M, Johnston ME, Kraeling RR

Animal reproduction science14 Aug 2017Cited by 10 (Europe PMC)

PMID28823417 (opens in a new tab)DOI10.1016/j.anireprosci.2017.08.003 (opens in a new tab)PepBankPUB-28823417
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

7 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mature gilts, estrus measures did not differ between placebo and triptorelin timing groups.

    In plain wordsIn pigs, estrus measures were similar between placebo and triptorelin timing groups.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeEstrus measures in experiment 2
    Study

    pign = 96

    Matrix-treated mature gilts
    Comparator
    Placebo and other triptorelin timings
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    200 μg · intravaginalAs given in this study (pig).

    Source sentences

    Summary
    Estrus measures did not differ (P>0.10) among treatments.
    1 context sentence
    Summary · context
    In experiment 2, gilts (n=96) received intravaginal treatment with 2mL of gel containing placebo (Control) at 96h, 200μg of triptorelin at 96h (TRP96), 120h (TRP120) or 144h (TRP144) after LMF.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In mature gilts, all triptorelin timing groups had shorter treatment-to-ovulation intervals than placebo.

    In plain wordsIn pigs, all triptorelin timing groups ovulated sooner after treatment than placebo recipients.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    DecreaseTreatment-to-ovulation interval
    Study

    pign = 96

    Matrix-treated mature gilts
    Comparator
    Placebo
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    200 μg · intravaginalAs given in this study (pig).

    Source sentences

    Summary
    The treatment to ovulation intervals for all triptorelin treatments were shorter (P<0.001) than Control.
    1 context sentence
    Summary · context
    In experiment 2, gilts (n=96) received intravaginal treatment with 2mL of gel containing placebo (Control) at 96h, 200μg of triptorelin at 96h (TRP96), 120h (TRP120) or 144h (TRP144) after LMF.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In mature gilts, triptorelin had no significant effect on estrus compared with placebo.

    In plain wordsIn pigs, triptorelin did not significantly change estrus compared with placebo.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeEstrus in experiment 3
    Study

    pign = 86

    Matrix-treated mature gilts
    Comparator
    Placebo
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    100-400 μg · intravaginalAs given in this study (pig).

    Source sentences

    Summary
    There was no effect of treatment (P>0.10) on estrus or on interval from LMF to estrus.
    1 context sentence
    Summary · context
    In experiment 3, gilts (n=86) received placebo (Control), 100μg (TRP100), 200μg (TRP200), or 400μg (TRP400) of triptorelin at 120h after LMF.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In mature gilts, triptorelin did not significantly change the interval from last Matrix feeding to estrus compared with placebo.

    In plain wordsIn pigs, triptorelin did not change the time from last Matrix feeding to estrus compared with placebo.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeLast Matrix feeding-to-estrus interval
    Study

    pign = 86

    Matrix-treated mature gilts
    Comparator
    Placebo
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    100-400 μg · intravaginalAs given in this study (pig).

    Source sentences

    Summary
    There was no effect of treatment (P>0.10) on estrus or on interval from LMF to estrus.
    1 context sentence
    Summary · context
    In experiment 3, gilts (n=86) received placebo (Control), 100μg (TRP100), 200μg (TRP200), or 400μg (TRP400) of triptorelin at 120h after LMF.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In mature gilts, triptorelin increased the proportion ovulating by 40, 48 and 56h compared with placebo.

    In plain wordsIn pigs, triptorelin increased the proportion ovulating by the measured times compared with placebo.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseOvulation by 40, 48 and 56 hours
    Study

    pign = 86

    Matrix-treated mature gilts
    Comparator
    Placebo
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    100-400 μg · intravaginalAs given in this study (pig).

    Source sentences

    Summary
    The proportion of gilts ovulating by 40, 48 and 56h after treatment increased (P<0.05) with triptorelin compared to Control.
    1 context sentence
    Summary · context
    In experiment 3, gilts (n=86) received placebo (Control), 100μg (TRP100), 200μg (TRP200), or 400μg (TRP400) of triptorelin at 120h after LMF.
  6. 06AnimalAnimal study (in vivo)Efficacy outcome

    In mature gilts, triptorelin at 120h increased ovulation within 32-56h compared with placebo and treatment at 96h.

    In plain wordsIn pigs, triptorelin at 120h increased timely ovulation compared with placebo and treatment at 96h.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseOvulation 32-56 hours after treatment at 120 hours
    Study

    pign: not reported in source

    Matrix-treated mature gilts
    Comparator
    Placebo and triptorelin at 96 hours
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    200 μg at 120 hours after last Matrix feeding · intravaginalAs given in this study (pig).

    Source sentences

    Summary
    The proportion of gilts ovulating 32-56h after treatment was greater for TRP120 and TRP144 (P<0.01) compared to other treatments.
    1 context sentence
    Summary · context
    In experiment 2, gilts (n=96) received intravaginal treatment with 2mL of gel containing placebo (Control) at 96h, 200μg of triptorelin at 96h (TRP96), 120h (TRP120) or 144h (TRP144) after LMF.
  7. 07AnimalAnimal study (in vivo)Efficacy outcome

    In mature gilts, triptorelin at 144h increased ovulation within 32-56h compared with placebo and treatment at 96h.

    In plain wordsIn pigs, triptorelin at 144h increased timely ovulation compared with placebo and treatment at 96h.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseOvulation 32-56 hours after treatment at 144 hours
    Study

    pign: not reported in source

    Matrix-treated mature gilts
    Comparator
    Placebo and triptorelin at 96 hours
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    200 μg at 144 hours after last Matrix feeding · intravaginalAs given in this study (pig).

    Source sentences

    Summary
    The proportion of gilts ovulating 32-56h after treatment was greater for TRP120 and TRP144 (P<0.01) compared to other treatments.
    1 context sentence
    Summary · context
    In experiment 2, gilts (n=96) received intravaginal treatment with 2mL of gel containing placebo (Control) at 96h, 200μg of triptorelin at 96h (TRP96), 120h (TRP120) or 144h (TRP144) after LMF.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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