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Study · Animal study (in vivo) · rat · 2018

3 results

Carnosine Treatment Diminished Oxidative Stress and Glycation Products in Serum and Tissues of D-Galactose-Treated Rats.

Aydin F, Kalaz EB, Kucukgergin C, Coban J, Dogru-Abbasoglu S, Uysal M

Current aging science1 Jan 2018Cited by 15 (Europe PMC)

PMID28676006 (opens in a new tab)DOI10.2174/1871530317666170703123519 (opens in a new tab)PepBankPUB-28676006
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    Carnosine significantly decreased serum glycooxidative stress in D-galactose-treated rats.

    In plain wordsIn rats given D-galactose, carnosine reduced serum glycooxidative stress compared with D-galactose alone.

    Peptide
    L-carnosine
    Outcome
    DecreaseSerum glycooxidative stress
    Study

    ratn: not reported in source

    D-galactose-treated male rats
    Comparator
    D-galactose alone
    Outcome group
    Aging markers · Aging and longevity
    Studied dose
    250 mg/kg daily, 5 days per week · intraperitoneal · two monthsAs given in this study (rat).

    Source sentences

    Summary
    CAR treatment was observed to decrease significantly glycooxidative stress in serum, liver and brain tissues of GAL-treated rats.
    2 context sentences
    Summary · context
    The effect of CAR supplementation on AGE levels and oxidative stress parameters was investigated in serum, liver and brain tissues in GAL-treated rats.
    Summary · context
    GAL (300 mg/kg; s.c.; 5 days per week) alone or together with CAR (250 mg/kg/daily; i.p.; 5 days per week) was applied to male rats for two months.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    Carnosine significantly decreased liver glycooxidative stress in D-galactose-treated rats.

    In plain wordsIn rats given D-galactose, carnosine reduced liver glycooxidative stress compared with D-galactose alone.

    Peptide
    L-carnosine
    Outcome
    DecreaseLiver glycooxidative stress
    Study

    ratn: not reported in source

    D-galactose-treated male rats
    Comparator
    D-galactose alone
    Outcome group
    Aging markers · Aging and longevity
    Studied dose
    250 mg/kg daily, 5 days per week · intraperitoneal · two monthsAs given in this study (rat).

    Source sentences

    Summary
    CAR treatment was observed to decrease significantly glycooxidative stress in serum, liver and brain tissues of GAL-treated rats.
    2 context sentences
    Summary · context
    The effect of CAR supplementation on AGE levels and oxidative stress parameters was investigated in serum, liver and brain tissues in GAL-treated rats.
    Summary · context
    GAL (300 mg/kg; s.c.; 5 days per week) alone or together with CAR (250 mg/kg/daily; i.p.; 5 days per week) was applied to male rats for two months.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    Carnosine significantly decreased brain glycooxidative stress in D-galactose-treated rats.

    In plain wordsIn rats given D-galactose, carnosine reduced brain glycooxidative stress compared with D-galactose alone.

    Peptide
    L-carnosine
    Outcome
    DecreaseBrain glycooxidative stress
    Study

    ratn: not reported in source

    D-galactose-treated male rats
    Comparator
    D-galactose alone
    Outcome group
    Aging markers · Aging and longevity
    Studied dose
    250 mg/kg daily, 5 days per week · intraperitoneal · two monthsAs given in this study (rat).

    Source sentences

    Summary
    CAR treatment was observed to decrease significantly glycooxidative stress in serum, liver and brain tissues of GAL-treated rats.
    2 context sentences
    Summary · context
    The effect of CAR supplementation on AGE levels and oxidative stress parameters was investigated in serum, liver and brain tissues in GAL-treated rats.
    Summary · context
    GAL (300 mg/kg; s.c.; 5 days per week) alone or together with CAR (250 mg/kg/daily; i.p.; 5 days per week) was applied to male rats for two months.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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