In patients assessed for cerebral ischemia, plasma NR2-peptide concentration decreased after a Cortexin treatment course.
In plain wordsIn patients assessed for cerebral ischemia, plasma NR2-peptide levels decreased after Cortexin treatment.
- Outcome
- DecreasePlasma NR2-peptide concentration
- Study
n: not reported in source
- Outcome group
- Neuroprotection · Nervous system and cognition
- Studied dose
- Dose not stated · 10 daysAs given in this study (human).
Measurements
- Plasma NR2-peptide concentration before cortexin treatment
- 8.5 ng/ml
- patients treated with cortexin, before the 10-day course
Source sentences
A decrease in NR2-peptide concentration (from 8.5 to 5,.9 ng/ml, p<0.0001) was noted in patients treated with cortexin after 10-day treatment course.
2 context sentences(design, population, supporting numbers)
To study blood plasma concentrations of NR2-peptide in patients with ischemic stroke (IS) to assess its diagnostic value as a biomarker of cerebral ischemia and determine the dynamics of the biomarker during treatment with cortexin.
Blood plasma concentration of NR2-peptide was measured in all patients at admission and after treatment.