In female rats, novel object recognition memory did not differ significantly across control, gonadectomy, triptorelin, and triptorelin-plus-estradiol groups.
In plain wordsIn female rats, object recognition memory did not differ significantly across control, gonadectomy, triptorelin, and triptorelin-plus-estradiol groups.
- Outcome
- No significant changeNovel object recognition memory in females
- Study
ratn: not reported in source
Gonadectomized Wistar rats- Comparator
- Control, gonadectomy alone, and triptorelin with or without estradiol
- Outcome group
- Cognition and memory · Nervous system and cognition
Source sentences
Furthermore, it was shown that gonadectomy and or treatment with triptorelin and sex steroids had no significant effect on novel object recognition memory in both female (P=0.472) and male rats (P=0.798).
3 context sentences(design, population, supporting numbers)
Additionally, triptorelin alone reduced the increased anxiety score in gonadectomized female rats, compared to group treated with both triptorelin and estradiol.
Four-month-old male and female Wistar rats were randomly assigned into 4 groups (in each sex): control rats (Cont), gonadectomized without treatment (GnX), gonadectomized treated with triptorelin, a GnRH agonist which reduces LH release eventually, (GnX+Tr), gonadectomized treated with triptorelin plus sex steroid hormone, estradiol in female and testosterone in male rats (GnX+Tr+S/T).
After 4 weeks treatment, anxiety score (elevated plus maze) and NOD were measured.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).