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Study · Measured the body's own peptide · 2017

4 results

Molecular cloning and characterization of kiss1 in Brandt's voles (Lasiopodomys brandtii).

Chen Y, Liu L, Li Z, Wang D, Li N, Song Y, Guo C, Liu X

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology18 Apr 2017Cited by 14 (Europe PMC)

PMID28427900 (opens in a new tab)DOI10.1016/j.cbpb.2017.04.006 (opens in a new tab)PepBankPUB-28427900
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In Brandt's voles, Kiss1 mRNA was expressed in ovary, testicle, small intestine, kidney, liver and hypothalamus, and was undetectable in other tissues.

    In plain wordsIn Brandt's voles, the body's own kisspeptin gene was active in some organs, including the hypothalamus, and not in others.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableKiss1 mRNA tissue distribution
    Study

    Brandt's volen: not reported in source

    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Source sentences

    Summary
    Kiss1 mRNA was specifically expressed in ovary, testicle, small intestine, kidney, liver and hypothalamus tissues, and was undetectable in other tissues, including pituitary, heart, adrenal gland, bladder and uterus.
    1 context sentence
    Summary · context
    In this study, kiss1 cDNA was cloned from the hypothalamus of Brandt's voles and kiss1 mRNA levels were investigated in different tissues, and at different developmental stages, using high-throughput real-time PCR.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In Brandt's voles, hypothalamic Kiss1 mRNA levels did not differ significantly between week 2 and week 4.

    In plain wordsIn Brandt's voles, the body's own kisspeptin gene activity in the hypothalamus did not change between week 2 and week 4.

    Peptide
    Kisspeptin-10
    Outcome
    No significant changeHypothalamic Kiss1 mRNA at weeks 2 and 4
    Study

    Brandt's volen: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    Kiss1 mRNA levels in the hypothalamus did not show a significant difference between week 2 and week 4
    1 context sentence
    Summary · context
    In this study, kiss1 cDNA was cloned from the hypothalamus of Brandt's voles and kiss1 mRNA levels were investigated in different tissues, and at different developmental stages, using high-throughput real-time PCR.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In Brandt's voles of both sexes, Kiss1 transcripts increased significantly 8 weeks after birth and stayed high in adults.

    In plain wordsIn Brandt's voles, the body's own kisspeptin gene became more active at 8 weeks of age and stayed high later in life.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseKiss1 transcripts at week 8
    Study

    Brandt's volen: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    Kiss1 transcripts significantly increased in both sexes 8weeks after birth, and then were maintained at high levels in adults
    1 context sentence
    Summary · context
    In this study, kiss1 cDNA was cloned from the hypothalamus of Brandt's voles and kiss1 mRNA levels were investigated in different tissues, and at different developmental stages, using high-throughput real-time PCR.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

Studies that did not test the peptide alone1

In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Kisspeptin-10.

  1. 04AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Other

    In Brandt's voles, the cloned kiss1 cDNA was 682 bp with a 405 bp open reading frame encoding 134 amino acids and a conserved kisspeptin‑10 region.

    In plain wordsIn Brandt's voles, the kiss1 gene was cloned and its product contains a conserved kisspeptin‑10 region.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicablekiss1 cDNA sequence
    Study

    Brandt's volen: not reported in source

    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Measurements

    cDNA length
    682 bp
    kiss1
    ORF length
    405 bp
    kiss1
    Encoded amino acids
    134 amino acids
    kiss1

    Source sentences

    Summary
    The full-length kiss1 cDNA was 682bp, containing an ORF of 405bp, encoding 134 amino acids with a conserved kisspeptin-10 region.
    1 context sentence
    Summary · context
    In this study, kiss1 cDNA was cloned from the hypothalamus of Brandt's voles and kiss1 mRNA levels were investigated in different tissues, and at different developmental stages, using high-throughput real-time PCR.

    In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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