Skip to content

Study · Randomized controlled trial · n = 165 · 2017

5 results

Effect of GnRHa ovulation trigger dose on follicular fluid characteristics and granulosa cell gene expression profiles.

Vuong TNL, Ho MT, Ha TQ, Jensen MB, Andersen CY, Humaidan P

Journal of assisted reproduction and genetics14 Feb 2017Cited by 6 (Europe PMC)

PMID28197932 (opens in a new tab)PMCIDPMC5401703 (opens in a new tab)DOI10.1007/s10815-017-0891-9 (opens in a new tab)PepBankPUB-28197932
Source linkPubMedAsk about this study
Jump to 5 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. 5 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In oocyte donors, follicular fluid progesterone did not differ significantly between triptorelin trigger doses.

    In plain wordsIn oocyte donors, follicular fluid progesterone was similar between triptorelin doses.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeFollicular fluid progesterone
    Study

    n = 165

    Comparator
    Other triptorelin trigger doses
    Analysis
    Primary
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Progesterone and oestradiol levels in FF did not differ significantly by trigger doses; findings were similar for 3βHSD, LHR and INHB-A gene expression in both cumulus and mural granulosa cells.
    3 context sentences
    Summary · context
    This single-centre, randomised, parallel, investigator-blinded trial was conducted in oocyte donors undergoing a single stimulation cycle at IVFMD, My Duc Hospital, Ho Chi Minh City, Vietnam, from August 2014 to March 2015.
    Summary · context
    A total of 165 women aged 18-35 years with body mass index 2, anti-Müllerian hormone >1.25 ng/mL, and antral follicle count ≥6 were randomised to three different triptorelin doses for trigger.
    Summary · context
    Moreover, luteinising hormone receptor (LHR), 3β-hydroxy-steroid-dehydrogenase (3ßHSD) and inhibin-Ba (INHB-A) gene expression in cumulus and mural granulosa cells were investigated in a subset of women from each group.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In oocyte donors, follicular fluid oestradiol did not differ significantly between triptorelin trigger doses.

    In plain wordsIn oocyte donors, follicular fluid oestradiol was similar between triptorelin doses.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeFollicular fluid oestradiol
    Study

    n = 165

    Comparator
    Other triptorelin trigger doses
    Analysis
    Primary
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Progesterone and oestradiol levels in FF did not differ significantly by trigger doses; findings were similar for 3βHSD, LHR and INHB-A gene expression in both cumulus and mural granulosa cells.
    3 context sentences
    Summary · context
    This single-centre, randomised, parallel, investigator-blinded trial was conducted in oocyte donors undergoing a single stimulation cycle at IVFMD, My Duc Hospital, Ho Chi Minh City, Vietnam, from August 2014 to March 2015.
    Summary · context
    A total of 165 women aged 18-35 years with body mass index 2, anti-Müllerian hormone >1.25 ng/mL, and antral follicle count ≥6 were randomised to three different triptorelin doses for trigger.
    Summary · context
    Moreover, luteinising hormone receptor (LHR), 3β-hydroxy-steroid-dehydrogenase (3ßHSD) and inhibin-Ba (INHB-A) gene expression in cumulus and mural granulosa cells were investigated in a subset of women from each group.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In oocyte donors, 3βHSD expression in cumulus and mural granulosa cells did not differ significantly between triptorelin doses.

    In plain wordsIn oocyte donors, granulosa cell 3βHSD expression was similar between triptorelin doses.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeGranulosa cell 3βHSD expression
    Study

    n: not reported in source

    Comparator
    Other triptorelin trigger doses
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Progesterone and oestradiol levels in FF did not differ significantly by trigger doses; findings were similar for 3βHSD, LHR and INHB-A gene expression in both cumulus and mural granulosa cells.
    3 context sentences
    Summary · context
    This single-centre, randomised, parallel, investigator-blinded trial was conducted in oocyte donors undergoing a single stimulation cycle at IVFMD, My Duc Hospital, Ho Chi Minh City, Vietnam, from August 2014 to March 2015.
    Summary · context
    A total of 165 women aged 18-35 years with body mass index 2, anti-Müllerian hormone >1.25 ng/mL, and antral follicle count ≥6 were randomised to three different triptorelin doses for trigger.
    Summary · context
    Moreover, luteinising hormone receptor (LHR), 3β-hydroxy-steroid-dehydrogenase (3ßHSD) and inhibin-Ba (INHB-A) gene expression in cumulus and mural granulosa cells were investigated in a subset of women from each group.
  4. 04HumanRandomized controlled trialEfficacy outcome

    In oocyte donors, LHR expression in cumulus and mural granulosa cells did not differ significantly between triptorelin doses.

    In plain wordsIn oocyte donors, granulosa cell LHR expression was similar between triptorelin doses.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeGranulosa cell LHR expression
    Study

    n: not reported in source

    Comparator
    Other triptorelin trigger doses
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Progesterone and oestradiol levels in FF did not differ significantly by trigger doses; findings were similar for 3βHSD, LHR and INHB-A gene expression in both cumulus and mural granulosa cells.
    3 context sentences
    Summary · context
    This single-centre, randomised, parallel, investigator-blinded trial was conducted in oocyte donors undergoing a single stimulation cycle at IVFMD, My Duc Hospital, Ho Chi Minh City, Vietnam, from August 2014 to March 2015.
    Summary · context
    A total of 165 women aged 18-35 years with body mass index 2, anti-Müllerian hormone >1.25 ng/mL, and antral follicle count ≥6 were randomised to three different triptorelin doses for trigger.
    Summary · context
    Moreover, luteinising hormone receptor (LHR), 3β-hydroxy-steroid-dehydrogenase (3ßHSD) and inhibin-Ba (INHB-A) gene expression in cumulus and mural granulosa cells were investigated in a subset of women from each group.
  5. 05HumanRandomized controlled trialEfficacy outcome

    In oocyte donors, INHB-A expression in cumulus and mural granulosa cells did not differ significantly between triptorelin doses.

    In plain wordsIn oocyte donors, granulosa cell INHB-A expression was similar between triptorelin doses.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeGranulosa cell INHB-A expression
    Study

    n: not reported in source

    Comparator
    Other triptorelin trigger doses
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Progesterone and oestradiol levels in FF did not differ significantly by trigger doses; findings were similar for 3βHSD, LHR and INHB-A gene expression in both cumulus and mural granulosa cells.
    3 context sentences
    Summary · context
    This single-centre, randomised, parallel, investigator-blinded trial was conducted in oocyte donors undergoing a single stimulation cycle at IVFMD, My Duc Hospital, Ho Chi Minh City, Vietnam, from August 2014 to March 2015.
    Summary · context
    A total of 165 women aged 18-35 years with body mass index 2, anti-Müllerian hormone >1.25 ng/mL, and antral follicle count ≥6 were randomised to three different triptorelin doses for trigger.
    Summary · context
    Moreover, luteinising hormone receptor (LHR), 3β-hydroxy-steroid-dehydrogenase (3ßHSD) and inhibin-Ba (INHB-A) gene expression in cumulus and mural granulosa cells were investigated in a subset of women from each group.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.