In healthy men, co-administration of GnIH did not change the LH response to kisspeptin‑10 (60-min LH AUC 6.2 versus 6.3 IU/h).
In plain wordsIn healthy men, adding GnIH did not change the rise in luteinizing hormone caused by kisspeptin‑10.
- Peptide
- Kisspeptin-10
- Outcome
- No significant changeKisspeptin-10-stimulated LH response with GnIH
- Study
n = 4
- Comparator
- Kisspeptin-10 with vehicle
- Outcome group
- Sex hormones and fertility · Endocrine and hormones
Measurements
- 60-min LH AUC
- 6.2 IU/h
- kisspeptin-10 alone
- 60-min LH AUC
- 6.3 IU/h
- kisspeptin-10 with GnIH
Source sentences
Kisspeptin-10-stimulated LH responses in men were not affected by GnIH co-administration (60-min AUC of LH 6·2 ± 0·8 IU/h with kisspeptin-10 alone, 6·3 ± 1·0 IU/h, kisspeptin-10 with GnIH, P = 0·72).
1 context sentence(design, population, supporting numbers)
Four men were administered kisspeptin-10 (0·3 μg/kg iv bolus) with simultaneous infusion of GnIH (50 μg/kg/h, iv for 3 h) or vehicle.
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.