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Study · Measured the body's own peptide · 2018

3 results

Serum humanin concentrations in women with pre-eclampsia compared to women with uncomplicated pregnancies.

Nikolakopoulos P, Tzimagiorgis G, Goulis DG, Chatzopoulou F, Zepiridis L, Vavilis D

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians9 Feb 2017Cited by 15 (Europe PMC)

PMID28110609 (opens in a new tab)DOI10.1080/14767058.2017.1285885 (opens in a new tab)PepBankPUB-28110609
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In pregnant women, serum humanin concentrations were higher in women with pre-eclampsia than in controls.

    In plain wordsIn pregnant women, the body's own humanin levels in blood were higher with pre-eclampsia than in women without it.

    Peptide
    Humanin
    Outcome
    IncreaseSerum humanin concentration in pre-eclampsia
    Study

    n = 71

    Comparator
    Women with uncomplicated pregnancies
    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Measurements

    serum humanin
    422.2 pg/ml
    pre-eclampsia group
    serum humanin
    319.1 pg/ml
    control group

    Source sentences

    Summary
    Humanin concentrations were higher in women with PE compared to controls (422.2 ± 33.5 vs. 319.1 ± 28.1 pg/ml, p = 0.023).
    1 context sentence
    Summary · context
    A case-control study where pregnant women (PE group, n = 37; control group, n = 34)

    This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In binary logistic analysis, higher serum humanin was associated with the presence of pre-eclampsia (odds ratio 1.003, 95% CI 1.000-1.006).

    In plain wordsIn pregnant women, higher natural humanin levels were linked to having pre-eclampsia.

    Peptide
    Humanin
    Outcome
    IncreaseAssociation of humanin with the presence of pre-eclampsia
    Study

    n = 71

    Comparator
    Women with uncomplicated pregnancies
    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    In a binary logistic analysis, humanin was associated with the presence of PE [odds ratio 1.003, 95% confidence interval (CI); 1.000-1.006].
    1 context sentence
    Summary · context
    A case-control study where pregnant women (PE group, n = 37; control group, n = 34)

    This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In ROC analysis, serum humanin discriminated women with pre-eclampsia from controls with an AUC of 0.639.

    In plain wordsIn pregnant women, the body's own humanin level in blood separated women with pre-eclampsia from controls with an AUC of 0.639.

    Peptide
    Humanin
    Outcome
    Not applicableDiscrimination of pre-eclampsia by serum humanin (ROC)
    Study

    n = 71

    Comparator
    Women with uncomplicated pregnancies
    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    The ability of humanin to discriminate between women with PE and controls was evaluated by receiver operation characteristics (ROC) analysis [area under the curve (AUC) 0.639, 95% CI; 0.510-0.768, p = 0.045].
    1 context sentence
    Summary · context
    A case-control study where pregnant women (PE group, n = 37; control group, n = 34)

    This result measures the body's own Humanin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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