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Study · Measured the body's own peptide · 2016

12 results

The expression of thymosin β4 in chronic hepatitis B combined nonalcoholic fatty liver disease.

Liang J, Cai W, Han T, Jing L, Ma Z, Gao Y

Medicine1 Dec 2016Cited by 7 (Europe PMC)

PMID28033294 (opens in a new tab)PMCIDPMC5207590 (opens in a new tab)DOI10.1097/md.0000000000005763 (opens in a new tab)PepBankPUB-28033294
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study12

No result from this study comes from a test of the peptide.

Natural levels measured12

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    Tβ4 levels in patients with chronic hepatitis B and NAFLD showed no statistical difference from those in the chronic hepatitis B control group.

    In plain wordsNatural Tβ4 levels were not different between patients with hepatitis B and fatty liver and patients with hepatitis B alone.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeSerum Tβ4 in CHB with NAFLD versus CHB
    Study

    n = 88

    Comparator
    CHB without NAFLD
    Outcome group
    Liver fat and liver function · Liver

    Source sentences

    Summary
    The Tβ4 levels in patients with CHB combined NAFLD showed no statistical difference when compared to the control group.
    1 context sentence
    Summary · context
    The study included 46 patients in the case group with CHB and NAFLD and 42 patients in the control group with CHB.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In patients with chronic hepatitis B and NAFLD, Tβ4 level had no correlation with ALT.

    In plain wordsIn these patients, the body's own Tβ4 level was not linked to ALT.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeTβ4 correlation with ALT
    Study

    n = 46

    Outcome group
    Liver fat and liver function · Liver

    Source sentences

    Summary
    the Tβ4 level had no correlation with ALT, AST, TG, FGP, hepatitis B virus (HBV)-DNA levels, and fat grading
    1 context sentence
    Summary · context
    The study included 46 patients in the case group with CHB and NAFLD and 42 patients in the control group with CHB.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In patients with chronic hepatitis B and NAFLD, Tβ4 level had no correlation with AST.

    In plain wordsIn these patients, the body's own Tβ4 level was not linked to AST.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeTβ4 correlation with AST
    Study

    n = 46

    Outcome group
    Liver fat and liver function · Liver

    Source sentences

    Summary
    the Tβ4 level had no correlation with ALT, AST, TG, FGP, hepatitis B virus (HBV)-DNA levels, and fat grading
    1 context sentence
    Summary · context
    The study included 46 patients in the case group with CHB and NAFLD and 42 patients in the control group with CHB.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  4. 04HumanEndogenous levelObservational studyOther

    In patients with chronic hepatitis B and NAFLD, Tβ4 level had no correlation with triglycerides.

    In plain wordsIn these patients, the body's own Tβ4 level was not linked to triglycerides.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeTβ4 correlation with triglycerides
    Study

    n = 46

    Outcome group
    Lipids · Liver

    Source sentences

    Summary
    the Tβ4 level had no correlation with ALT, AST, TG, FGP, hepatitis B virus (HBV)-DNA levels, and fat grading
    1 context sentence
    Summary · context
    The study included 46 patients in the case group with CHB and NAFLD and 42 patients in the control group with CHB.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  5. 05HumanEndogenous levelObservational studyOther

    In patients with chronic hepatitis B and NAFLD, Tβ4 level had no correlation with FGP.

    In plain wordsIn these patients, the body's own Tβ4 level was not linked to FGP.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeTβ4 correlation with FGP
    Study

    n = 46

    Outcome group
    Liver fat and liver function · Liver

    Source sentences

    Summary
    the Tβ4 level had no correlation with ALT, AST, TG, FGP, hepatitis B virus (HBV)-DNA levels, and fat grading
    1 context sentence
    Summary · context
    The study included 46 patients in the case group with CHB and NAFLD and 42 patients in the control group with CHB.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  6. 06HumanEndogenous levelObservational studyOther

    In patients with chronic hepatitis B and NAFLD, Tβ4 level had no correlation with hepatitis B virus DNA levels.

    In plain wordsIn these patients, the body's own Tβ4 level was not linked to hepatitis B virus DNA levels.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeTβ4 correlation with HBV-DNA level
    Study

    n = 46

    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    the Tβ4 level had no correlation with ALT, AST, TG, FGP, hepatitis B virus (HBV)-DNA levels, and fat grading
    1 context sentence
    Summary · context
    The study included 46 patients in the case group with CHB and NAFLD and 42 patients in the control group with CHB.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  7. 07HumanEndogenous levelObservational studyOther

    In patients with chronic hepatitis B and NAFLD, Tβ4 level had no correlation with fat grading.

    In plain wordsIn these patients, the body's own Tβ4 level was not linked to the grade of liver fat.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeTβ4 correlation with fat grading
    Study

    n = 46

    Outcome group
    Liver fat and liver function · Liver

    Source sentences

    Summary
    the Tβ4 level had no correlation with ALT, AST, TG, FGP, hepatitis B virus (HBV)-DNA levels, and fat grading
    1 context sentence
    Summary · context
    The study included 46 patients in the case group with CHB and NAFLD and 42 patients in the control group with CHB.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  8. 08HumanEndogenous levelObservational studyOther

    In patients with chronic hepatitis B and NAFLD, Tβ4 level had a negative correlation with inflammation score (P <0.01).

    In plain wordsIn these patients, a higher level of the body's own Tβ4 was linked to a lower liver inflammation score.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    DecreaseTβ4 correlation with inflammation score
    Study

    n = 46

    Outcome group
    Inflammation markers · Liver

    Source sentences

    Summary
    but had negative correlation with inflammation score and fibrosis score (P <0.01).
    1 context sentence
    Summary · context
    The study included 46 patients in the case group with CHB and NAFLD and 42 patients in the control group with CHB.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  9. 09HumanEndogenous levelObservational studyOther

    In patients with chronic hepatitis B and NAFLD, Tβ4 level had a negative correlation with fibrosis score (P <0.01).

    In plain wordsIn these patients, a higher level of the body's own Tβ4 was linked to a lower liver fibrosis score.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    DecreaseTβ4 correlation with fibrosis score
    Study

    n = 46

    Outcome group
    Liver fat and liver function · Liver

    Source sentences

    Summary
    but had negative correlation with inflammation score and fibrosis score (P <0.01).
    1 context sentence
    Summary · context
    The study included 46 patients in the case group with CHB and NAFLD and 42 patients in the control group with CHB.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  10. 10HumanEndogenous levelObservational studyOther

    Tβ4 immunohistochemical expression intensity differed significantly between the severe and slight inflammation fibrosis groups.

    In plain wordsNatural Tβ4 staining in liver tissue differed between patients with severe and slight inflammation and fibrosis.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Direction not reportedLiver Tβ4 expression by inflammation fibrosis severity
    Study

    n: not reported in source

    Outcome group
    Liver fat and liver function · Liver

    Source sentences

    Summary
    The immunohistochemical results of hepatic tissues showed that the expression intensity of severe inflammation fibrosis group had statistical significance compared with that of slight group
    1 context sentence
    Summary · context
    The study included 46 patients in the case group with CHB and NAFLD and 42 patients in the control group with CHB.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  11. 11HumanEndogenous levelObservational studyOther

    Serum Tβ4 expression negatively correlated with TNF-α expression.

    In plain wordsA higher level of the body's own Tβ4 in blood was linked to a lower TNF-α level.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    DecreaseSerum Tβ4 correlation with TNF-α
    Study

    n: not reported in source

    Outcome group
    Inflammation markers · Immune and inflammation

    Source sentences

    Summary
    the Tβ4 expression both in serum and in liver tissue negatively correlated with TNF-α expression.
    1 context sentence
    Summary · context
    The study included 46 patients in the case group with CHB and NAFLD and 42 patients in the control group with CHB.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  12. 12HumanEndogenous levelObservational studyOther

    Tβ4 expression in liver tissue negatively correlated with TNF-α expression.

    In plain wordsA higher level of the body's own Tβ4 in liver tissue was linked to a lower TNF-α level.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    DecreaseLiver tissue Tβ4 correlation with TNF-α
    Study

    n: not reported in source

    Outcome group
    Inflammation markers · Immune and inflammation

    Source sentences

    Summary
    the Tβ4 expression both in serum and in liver tissue negatively correlated with TNF-α expression.
    1 context sentence
    Summary · context
    The study included 46 patients in the case group with CHB and NAFLD and 42 patients in the control group with CHB.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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