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Study · Animal study (in vivo) · rat · 2017

5 results

Investigation of the effects of kisspeptin-10 in methionine-induced lipid peroxidation in testicle tissue of young rats.

Akkaya H, Eyuboglu S, Erkanlı Senturk G, Yilmaz B

Journal of biochemical and molecular toxicology30 Nov 2016Cited by 8 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In young rats with methionine-induced testicular lipid peroxidation, kisspeptin‑10 did not significantly affect spermatogenic cells in seminiferous tubules.

    In plain wordsIn young rats, kisspeptin‑10 did not significantly change spermatogenic cells in the testicle tubules.

    Outcome
    No significant changeSpermatogenic cells in seminiferous tubules
    Study

    ratn: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Kisspeptin-10 did not significantly affect spermatogenic cells in seminiferous tubules.
    1 context sentence
    Summary · context
    We have examined possible effects of kisspeptin-10 on the structural damage produced by methionine-induced lipid peroxidation in testicle tissue of young rats.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In young rats with methionine-induced testicular lipid peroxidation, catalase activity was higher in the kisspeptin‑10 group than in the other groups.

    In plain wordsIn young rats, catalase activity in the testicle was higher with kisspeptin‑10 than in the other groups.

    Outcome
    IncreaseCatalase enzyme activity
    Study

    ratn: not reported in source

    Comparator
    Other groups
    Outcome group
    Oxidative stress · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Catalase enzyme activity increased in the kisspeptin-10 group (P < 0.01) as compared with the other groups.
    1 context sentence
    Summary · context
    We have examined possible effects of kisspeptin-10 on the structural damage produced by methionine-induced lipid peroxidation in testicle tissue of young rats.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In young rats with methionine-induced testicular lipid peroxidation, catalase mRNA expression was higher in the kisspeptin group than in the methionine group.

    In plain wordsIn young rats, catalase gene activity was higher with kisspeptin than in the methionine group.

    Outcome
    IncreaseCatalase mRNA expression
    Study

    ratn: not reported in source

    Comparator
    Methionine group
    Outcome group
    Oxidative stress · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Catalase mRNA expression was decreased in the methionine group as compared with the kisspeptin group (P < 0.001).
    1 context sentence
    Summary · context
    We have examined possible effects of kisspeptin-10 on the structural damage produced by methionine-induced lipid peroxidation in testicle tissue of young rats.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In young rats with methionine-induced testicular lipid peroxidation, total superoxide dismutase activity was higher in the kisspeptin group than in the methionine group.

    In plain wordsIn young rats, superoxide dismutase activity was higher with kisspeptin than in the methionine group.

    Outcome
    IncreaseTotal superoxide dismutase activity
    Study

    ratn: not reported in source

    Comparator
    Methionine group
    Outcome group
    Oxidative stress · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Total superoxide dismutase enzyme activity and superoxide dismutase mRNA expression were increased in the kisspeptin group as compared with the methionine group (P < 0.05).
    1 context sentence
    Summary · context
    We have examined possible effects of kisspeptin-10 on the structural damage produced by methionine-induced lipid peroxidation in testicle tissue of young rats.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In young rats with methionine-induced testicular lipid peroxidation, superoxide dismutase mRNA expression was higher in the kisspeptin group than in the methionine group.

    In plain wordsIn young rats, superoxide dismutase gene activity was higher with kisspeptin than in the methionine group.

    Outcome
    IncreaseSuperoxide dismutase mRNA expression
    Study

    ratn: not reported in source

    Comparator
    Methionine group
    Outcome group
    Oxidative stress · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Total superoxide dismutase enzyme activity and superoxide dismutase mRNA expression were increased in the kisspeptin group as compared with the methionine group (P < 0.05).
    1 context sentence
    Summary · context
    We have examined possible effects of kisspeptin-10 on the structural damage produced by methionine-induced lipid peroxidation in testicle tissue of young rats.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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