In skeletal muscle cells challenged with H2O2 after poloxamer 188 pre-treatment, expression of thymosin beta‑4 stayed largely stable.
In plain wordsIn muscle cells, the body's own thymosin beta‑4 levels stayed largely stable after poloxamer 188 pre-treatment and oxidative stress.
- Peptide
- Thymosin beta-4 (human)
- Outcome
- No significant changeTβ4 expression under oxidative challenge with P188 pre-treatment
- Study
n: not reported in source
skeletal muscle cells- Outcome group
- Muscle injury and repair · Musculoskeletal
Source sentences
The actin polymerization dynamics largely remained stable in term of the expression of cofilin, thymosin beta 4 and profilin.
2 context sentences(design, population, supporting numbers)
It was found that with 1 mM P188 pre-treatment for 1 h, skeletal muscle cells could maintain their compressive damage threshold.
In this study, we investigated the preventive effect of poloxamer 188 (P188) on skeletal muscle cells against extrinsic oxidative challenges (H2O2).
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.